Ch3

Question 1

What do the receptors of the innate immune system help immune cells recognize?

Answer 1

Self receptors: human cells
non-self receptors: pathogens
Altered-self receptors: sick cells (infected or cancerous cells)

Question 2

What is a lectin receptor?

Answer 2

It is a peptide receptor that recognizes carbohydrates
Peptidoglycan (bacteria)
Lipopolysaccharide (LPS)

Question 3

Pattern recognition receptors

Answer 3

PAMPS
DAMPS

Question 4

PAMP stands for…

Answer 4

pathogen associated molecular pattern

Question 5

DAMP stands for..
What do DAMPs do

Answer 5

damage-associated molecular pattern
recognize damaged cells like cancerous or infected cells

Question 6

scavenger receptors

Answer 6

a PAMP receptor that removes dead/dying cells

Question 7

SR-E receptors

Answer 7

lectin type receptors

Question 8

Manose receptors

Answer 8

a very common PAMP receptor with 10 domains. One domain is the c domain (c-type lectin domain) and the mechanism needs calcium

Question 9

Toll-like Receptors

Answer 9

PAMP receptors; signaling receptors
TLRs 1-10 same as CD281-CD290

Question 10

What does the TLR4 complex consist of

Answer 10

CD-14
MD-2; soluble binds LPS

Question 11

What is LBP and what does it do

Answer 11

lipopolysaccharide binding protein; binds LPS