Ch14: Olfaction Flashcards
What is an odor?
odorants are molecules that olfactory receptors can respond to
Describe the detection and identification of odors
perceived intensity of odor increases as concentration of odor increases; change in concentration may change quality of odor (ex: 1-heptanol)
What are the measuring thresholds?
detection and difference (75%; JND)
How does perception of odor change with age and smoking?
smoking exacerbates age-related decline in olfaction
“lack of smell”?
anosmia– occurs as you get older; can lead to hypertension (high BP)
Describe adaptation
detects novel stimuli more readily but w repeated exposure, olfactory system responds less strongly
cross-adaptation
similar odorants can experience adaptation; if the odorants are molecularly similar (ex: only one diff in carbon chain length, investigation time remains low)
what kind of mapping does olfactory system show?
chemotopic mapping (similar molecular structures will be processed in adjacent regions)
what are the two pathways into and through the brain?
orthonasal and retronasal (through the pharynx when chewing food)
describe the pathway that olfactory info travels?
through nasal cavity, stirred around by turbinates (bony structures), mucus that covers epithelium; if dissolved, interact w cilia where the receptors are (lock and key); if it binds w receptor, activates G protein mediated pathway that opens ion channels, depolarizing the cell; once threshold is reached, action potentials will be sent along the axon; axons of ORN bundle together to form the olfactory nerve
cells in the olfactory epithelium
basal cells generate new ORN’s constantly; Bowman’s gland produces mucus; supporting cells– structural support
cribiform plate
porous bony structure; w head trauma can experience anosmia, shearing off the axons
what happens when the olfactory nerves pass through the cribiform plate?
olfactory bulb (in the brain); glomeruli synapses ORNs to mitral and tufted cells (output of bulb); axons bundle together– olfactory tract; send signals higher into the brain
transduction
350 diff types of receptors; open calcium and sodium ion channels
Explain what a population code is and its role in olfaction.
unique pattern of responses for each odorant across the receptor types