Ch.13, cont Flashcards
default network regions and functions and discovery, hyperactive problems
discovered: through rsFMRI active most when in non-demanding tasks
region: interacting regions of the frontal and parietal lobes that have very highly correlated activity
activity reduces in demanding tasks
hyperactive= Major depressive disorder/rumination
important regions of frontal lobe development
- medial regions of frontal lobe
- posterior cingulate cortex
- lateral parietal lobe
When are the frontal lobe regions (3) and reduction in cortical thickness the same as an adult and what does it correlate to
age 13, correlates with intelligence
ACEs
ACEs are additive
linked to chronic mental health, health problems, substance use issues
stats/aces
two or more ACES: 50x more likely to acquire addictions/attempt suicide
women with two or more ACES: 5x more likely to have been sexually assaulted by age 50
Romanian orphans case longterm effects
unwanted children in orphanages: long-term suffered from chronic infections, intellectual, social, and motor impairements
age 2 vs later adoption affects on specific brain regions, romanian orphans
before 2 years: made recovery
after 2: smaller brain size, reduction in gray/white matter, unresolved cognitive/behavioural problems
= PFC, HPC, amygdala
ACES in early life and prenatally and brain volume
- increased size of amygdala
- decreased HPC VOLUME
Which week is the CNS very sensitive?
week 4-6, when neural tube is forming
Hebb’s rat experiment
reared a group of rats in his kitchen: had larger more complex synapses due to environment enrichment
performed better on the Hebbs/William maze task than lab-reared controls
tactile stimulation/ kangaroo care
3 weeks of tactile stimulation in infancy createsd larger more complex and richer synapses
Integrative Theory, Tooley
stress = accelerates brain development
faster maturation = reduced plasticity
High SES children = have the advantage of slower segregation of connectivity into adult networks
