Ch10 CNS Effects of Inhaled Anesthetics Flashcards
What do inhaled anesthetics do to EEG patterns?
They slow down and make EEG waves bigger and slower.
At what anesthetic concentration does burst suppression occur?
At 1.25 MAC.
How does nitrous oxide affect the MAC curve?
It shifts the MAC curve to the right but does not affect EEG.
What is the spectral edge frequency?
It measures the highest frequency of brain activity.
What happens to spectral edge frequency during anesthesia?
It decreases, indicating lower frequency brain activity.
What can precipitate convulsions during anesthesia?
Hypocarbia, higher concentrations of anesthetics, and pre-existing epilepsy.
What are somatosensory evoked potentials (SSEPs) used for?
To measure nerve impulse transmission and monitor spinal cord protection.
What effect do potent inhaled anesthetics have on SSEPs?
They can affect the amplitude or latency of the evoked potential.
What is the purpose of deliberate hypotension during surgeries?
To reduce blood loss.
What do potent inhaled anesthetics do to cerebral metabolism?
They decrease metabolism.
What effect do potent inhaled anesthetics generally have on cerebral blood flow?
Cerebral blood flow may stay constant or increase.
What is the relationship between anesthetic concentration and intracranial pressure?
Intracranial pressure may increase at higher anesthetic concentrations.
Which anesthetic is noted for better protection against ischemic insults?
Sevoflurane.
What is the significance of the protective effect of inhaled anesthetics?
It is significant, with potential benefits for patients undergoing neurosurgery.
True or False: A flat EEG during anesthesia indicates that the patient is dead.
False.
Fill in the blank: The protective effect of inhaled anesthetics is ______ dependent.
dose.
What is a key consideration when choosing anesthetics for neurosurgery?
The specific needs and goals of the surgery.
What is the goal regarding anesthetic depth and cerebral perfusion?
To achieve adequate anesthesia without compromising cerebral perfusion.
What is the effect of nitrous oxide on SSEPs when combined with other anesthetics?
It may cause more profound depression.
What are the potential outcomes of using desflurane during temporary middle cerebral artery occlusion?
Higher PO2 and fewer postoperative neurologic deficits.
What is the significance level of the difference between the two approaches mentioned?
Did not reach significance
The significance level indicates that while there is a difference, it is not statistically significant.
What protective effect do potent inhaled anesthetics have?
Relative to drugs like atomidate or thiopental
Potent inhaled anesthetics may provide better protection for patients compared to certain intravenous anesthetics.
What does the metabolic effect of inhaled anesthetics depend on?
Dose related effect on metabolic rate
The effect on metabolism is influenced by the amount of inhaled anesthetic administered.
What was shown by the study regarding inhaled anesthetics and EEG?
Changes in human dynamics and metabolism
The study indicated that adding inhaled anesthetics to propofol, which produces EEG silence, can affect human dynamics.
