Ch1 Hoffbrand-Moss Flashcards
What is haemopoiesis?
blood cell formation
What is myelopoiesis?
granulocyte and monocyte formatiion
What site is the only source of new blood cells during childhood and adult life?
bone marrow
Where does haemopoiesis take place during the first 2 months after conception?
yolk sac
Where does haemopoiesis take place between 2-7 months after conception?
liver,spleen
Which growth factors act on stromal cells?
IL-1 and TNF
Which growth factors act on pluripotential stem cells?
SCF, FLT3-L, VEGF
Which growth factors act on multipotential progenitor cells?
IL-3, GM-CSF, IL-6, G-CSF, Thrombopoietin
Which growth factors act on committed progenitor cells?
G-CSF, M-CSF, IL-5, erythropoietin, thrombopoietin