Ch. 9 Inflammation, Tissue, Repair, & Wound Healing

Question 1

incision

Answer 1

cutting or sharp instrument; wound edges in close approximation & aligned

Question 2

contusion

Answer 2

blunt instrument, overlying skin remains intact, with injury to underlying soft tissue; possible resultant bruising and/or hematoma

Question 3

abrasion

Answer 3

friction; rubbing or scraping epidermal layers of skin; top layer of skin abraded

Question 4

laceration

Answer 4

tearing of skin & tissue with blunt or irregular instrument; tissue not aligned, often with loose flaps of skin & tissue

Question 5

puncture

Answer 5

blunt or sharp instrument puncturing the skin; intentional ( such as venipuncture ) or accidental

Question 6

penetrating

Answer 6

foreign object entering the skin or mucous membrane & lodging in underlying tissue; fragments possibly scattering throughout tissues

Question 7

avulsion

Answer 7

tearing a structure from normal anatomic position; possible damage to blood vessels, nerves, & other structures

Question 8

chemical

Answer 8

toxic agents such as drugs, alcohols, metals & substances released from cellular necrosis

Question 9

thermal

Answer 9

high or low temperatures; cellular necrosis as a possible result

Question 10

irradiation

Answer 10

ultraviolet light or radiation exposure

Question 11

tissue repair

Answer 11

a response to tissue injury & represents an attempt to maintain normal body structure & region

Question 12

tissue regeneration

Answer 12

replacement of injured tissue with cells of the same type

Question 13

fibrous tissue repair

Answer 13

repair by replacement with connective tissue & scar formation

Question 14

granulation tissue

Answer 14

• glistening red, moist connective tissue that contains newly formed capillaries, proliferating fibroblasts, & residual inflammatory cells
• scar formation builds on the granulation tissue framework of new vessels & loose ECM

Question 15

1st stage of wound healing

Answer 15

inflammatory phase: begins at the time of injury; blood clot forms, migration of phagocytic WBCs into the wound site

Question 16

2nd stage of wound healing

Answer 16

proliferative phase: new tissue fills the wound

Question 17

fibroblasts

Answer 17

a connective tissue cell that synthesizes & secretes collagen, proteoglycans, & glycoproteins needed for wound healing

Question 18

3rd stage of wound healing

Answer 18

wound contraction & remodeling phase: about 3 weeks after injury; fibrous scar develops; remodeling of scar tissue

Question 19

causes of impaired wound healing:

Answer 19

• malnutrition
• impaired blood flow & oxygen delivery
• impaired inflammation & immune responses
• infection
• wound separation
• foreign bodies
• age effects

Question 20

serous

Answer 20

watery fluid low in protein

Question 21

hemorrhagic

Answer 21

leakage of RBC from the capillaries

Question 22

fibrinous

Answer 22

large amounts of fibrinogen, forms a thick & sticky meshwork

Question 23

membranous

Answer 23

develops on mucous membranes surfaces & are composed of necrotic cells enmeshed in fibro-purulent exudate

Question 24

abscess

Answer 24

localized area of inflammation containing purulent exudate

Question 25

ulceration

Answer 25

epithelial surface becomes necrotic