Ch 8 Flashcards
Somatic effects :
All cells in body other than sex cells
Genetic effects:
Effects to the sperm and the ovum
Early effects:
The biological effects show up minutes, hours, days, or weeks after exposure
Late effects:
Biological effects that show up months or years after the exposure
Early non stochastic / deterministic effects
Biological effects will occur minutes, hours, days, or weeks after whole body exposure to a large dose or radiation
(Does not occur at diagnostic level)
The severity of biological effects and dose are ___ related
Directly
Dose response curve threshold is :
Dose radiation received before biological response occurs
As the linear response increases :
Increased dose and increased biological reaction
Early biological responsible reactions includes :
Nausea, fatigue, erthemya, epilation, blood disorders, sterility, dry and moist desquamation
Affects GI system, hemopoatic system, integumentary system
Protracted dose:
A radiation dose delivered continuously over a very long period of time at very low dose
Ex. Brady therapy - radiation seeds
Fractionated dose:
Dose that is delivered in equal fractions separated over 24hrs (rad therapy)
Gives cells a chance to heal and repair
ARS ( acute radiation sickness) is caused by:
Large whole body exposure dose delivered in a short amount of time
3 possible ARS syndromes :
Hemopoatic syndrome
Gastrointestinal syndrome
Cerebral vascular system
4 responses to ARS in order :
Prodromal
Latent period
Manifest illness
Death or recovery
Prodromal
Occurs hrs after exposure of 1 Gyt or more
Symptoms last hrs to a few days
Severity of symptoms increase as dose increases
Includes nausea vomitting diarrhea fatigue lukopenia
