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NAPLEX Review UWorld > Ch 6: Drug Formulations & Patient Counseling > Flashcards

Ch 6: Drug Formulations & Patient Counseling Flashcards

1
Q

What are the benefits Osmotic controlled-release oral delivery systems (OROS)?

A

Decreased frequency of drug administration due to its extended-release formulation

Afast drug delivery due to the rapid dissolution of the overcoat, which allows for a quicker onset of action

Reduced fluctuations in serum drug levels due to the controlled release of drug as the OROS is activated

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2
Q

Brand:Generic

Detrol LA

A

tolterodine

Tx overactive bladder symptoms

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3
Q

Brand:Generic

Rapamune

A

sirolimus

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4
Q

Brand:Generic

Suprax

A

cefixime

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5
Q

Brand:Generic

Mycelex

A

clotrimazole

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6
Q

Brand:Generic

Cepacol

A

benzocaine/menthol

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7
Q

Brand:Generic

Nurtec

A

rimegepant

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8
Q

Brand:Generic

Remeron SolTab

A

mirtazepine ODT

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9
Q

Brand:Generic

Zyprexa Zydis

A

olanzapine ODT

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10
Q

Brand:Generic

Edluar

A

zolpidem SL

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11
Q

Brand:Generic

Subsys

A

fentanyl SL spray

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12
Q

Brand:Generic

Actiq

A

fentanyl lozenge

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13
Q

Brand:Generic

Fentora

A

fentanyl buccal tab

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14
Q

Drugs that can be sprinkle on applesauce

A

Adderall XR - dextroamphetamine/amphetamine ER

Coreg CR - carvedilol

Dexilant - dexlansoprazole

Focalin XR - dexmethylphenidate

Namenda XR - memantine

Nexium - esomeprazole

Ritaline LA - methylphenidate

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15
Q

What can this drug be mix with?

Cambia (diclofenac potassium)

powder

A

water

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16
Q

What can this drug be mix with?

Creon

and other pancreatic enzyme products

A

on soft food w/ low pH:
applesauce
pureed pears or banana

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17
Q

What can this drug be mix with?

Depakote Sprinkles (valproic acid)

A

soft food

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18
Q

What can this drug be mix with?

Kadian (morphine)

A

applesauce or soft food

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19
Q

What can this drug be mix with?

potassium chloride ER

Capsules

A

applesauce or pudding

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20
Q

What can this drug be mix with?

Questran (cholestyramine)

Including Questran Light

A

2-6 oz of water or non-carbonated liquid

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21
Q

What can this drug be mix with?

Singulair (montelukast)

A

5 ml baby formula or breast milk OR
In a spoonful of applesauce, carrots, rice, or ice cream

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22
Q

What can this drug be mix with?

Vyvanse (lisdexamfetamine)

A

water
yogurt
orange juice

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23
Q

Which sweetener produces gas, cramping, & bloating?

In sensitive pts including those w/ IBS

A

Sorbitol

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24
Q

Which sweetener is dangerous for those w/ phenylketonuria (PKU)?

A

phenylalanine

Use in ODT, chewable, & granule

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25
Q

Brand: Generic

Invega Sustenna

& Invega Trinza

A

paliperidone

LA IM injection

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26
Q

Brand: Generic

Risperdal Consta

A

reperidone

LA IM injection

27
Q

Brand: Generic

Vivtral

A

naltrexone

LA IM injection

28
Q

Brand: Generic

Zyprexa Relprevv

A

olanzapine

LA IM injection

29
Q

Self-Administered Injections

Which ones require refrigeration?

A

glatiramer (Copaxone)
etanercept (Enbrel)
adalimumab (Humira)
certolizumab pegol (Cimzia)
golimumab (Simponi)
teriparatide (Forteo)
abaloparatide (Tymlos)

30
Q

Self-Administered Injections

Which ones does not require refrigeration?

A

enoxaparin (Lovenox)
fondaparinux (Arixtra)
methotrexate (Otrexup)
sumatriptan (Imitrex, Zembrace, SymTouch)

31
Q

Self-Administered Injections

Which injection should you not rub the skin and why?

A

Anticoagulant injections (e.g. enoxaparin, fondaparinux)
Can cause severe bruising

32
Q

Which injections should not be shaken?

A

Monoclonal Antibodies

33
Q

Most patches can be applied to?

A

Chest (upper)
Back (upper & lower)
Upper arm (on the part facing out)
Flanks (sides of the body, abdomen level)

34
Q

Patch Site Exception

Exelon

A

Normal sites except not on the flanks

Rivastigmine

35
Q

Patch Site Exception

Butrans

A

Normal sites except the flank is chest level

36
Q

Patch Site Exception

Which patches are applied the affected area?

A

diclofenac (Flector)
lidocaine (Lidoderm, Salonpas)
capsaicin (Qutenza)

37
Q

Patch Site Exception

Where do you apply Daytrana?

A

hip

methylphenidate

38
Q

Patch Site Exception

Where do you not apply estrogen patches?

A

breast

39
Q

Patch Site Exception

Where do you not apply testosterone patches?

A

scrotum

40
Q

Which patches can be applied to the buttock?

A

Xulane

oxybutynin (Oxytrol)

Vivelle-Dot

41
Q

Which patches are applied twice daily?

A

diclofenac (Flector)

42
Q

Which patches are applied daily ?

A

methylphenidate (Daytrana) - 2 hrs prior to school

nicotine (NicoDerm CQ)

rivastigmine (Exelon)

rotigotine (Neupro)

selegiline (Emsam)

testosterone (Androderm) - nightly

43
Q

Which patches are applied Q72H ?

A

fentanyl (Duragesic) - can be change to Q48H if it wears off after 48 hours

scopolamine (Transderm Scop): Q72H PRN

44
Q

Which patches are applied twice weekly?

A

estradiol (Alova, Vivelle-Dot)

oxybutynin (Oxytrol)

45
Q

Which patches are applied weekly?

A

donepezil (Adlarity)

buprenorphine (Butrans)

clonidine (Catapres-TTS)

estradiol (Climara) - continuous or cyclic

estradiol/levonorgestrel

ethinyl estradiol/norelgestromin (Xulane, Zafemy) - cyclic

ethinyl estradiol/levonorgestrel (Twirla) - cyclic

Cyclic - 3 weeks on, 1 week off

46
Q

Lidocaine patch instruction

A

1-3 patches daily PRN on for 12 hrs, off for 12 hrs

Lidoderm

47
Q

nitroglycerin patches

A

1 patch daily, on for 12-14 hrs, off for 10-12 hrs

48
Q

Which patches can be cut?

A

Lidoderm & Qutenza

49
Q

What can be applied for skin irritation from the patch?

A

topical steroids (e.g. hydrocortisone) after removing the patch

50
Q

Which patches has to be removed before an MRI?

A

clonidine (Catapres-TTS)

rotigotine (Neupro)

scopolamine (Transderm Scop)

testosterone (Androderm)

51
Q

Which patch can be covered by tape and what type of tape?

A

fentanyl & buprenorphine (Butrans)

Bioclusive or Tegaderm

52
Q

Which patches should be flush?

A

narcotic patches (e.g. fentanyl, Butrans)

Daytrana

53
Q

Nasal Spray Counseling

Before use

A

Shake gently

Prime - 1st use or haven’t used within 7-14 days

Blow nose before use

54
Q

Nasal Spray Counseling

Using

A

Close one nostril

Breathe in through your nose then pres firmly & quickly down on applicator

Breathe out through mouth

Use for the labeled # of spray and discard, even if it’s not empty

Do not blow your nose after spray

55
Q

Eye Drop Counseling

Before

A

Shake a few times

Gels - inverted & shaken once

56
Q

Eye Drop Counseling

After

A

Close eyes

Press a finger between eye & the top of the nose for 1 minute

57
Q

How many minutes between drops?

A

5 minutes between doses

5-10 minutes between medications

10 minutes between gels

58
Q

Drops w/ benzalkonium chloride (BAK)

A

remove soft contacts & wait 15 minutes

59
Q

Ear drop administration for adults

A

Pull ear up & back

60
Q

Ear drop administration for childrens < 3 y/o

A

Pull ear down & back

61
Q

Ear drops

How long do you stay on your side?

A

5 minutes

62
Q

What is the position for administrating enemas?

A

Lying on the left side

Left leg extended

Right leg flexed forward

Insert applicator tip slightly toward the navel

63
Q

How long does the patient have to remainin in the same position after an enema?

A

30 minutes

64
Q

How long do you need to keep the suppository in?

A

1-3 hrs

NAPLEX Review UWorld (17 decks)

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