Ch. 58 Drugs Affecting GI Motility Flashcards
1
Q
Define Laxatives
A
short-term relief of constipation
2
Q
What do chemical stimulants do?
A
chemically irritate the lining of the GI tract
3
Q
what do bulk stimulants do?
A
cause the fecal matter to increase in bulk
4
Q
what do lubricants do?
A
help the intestinal contents move more smoothly
5
Q
what is the prototype of chemical stimulant
A
Castor Oil
6
Q
what is the prototype of bulk stimulant
A
Magnesium Citrate
7
Q
what is the prototype of lubricants
A
Mineral Oil
8
Q
Mineral Oil: Indications
A
- short term relief of constipation
- prevent straining when clinically undesirable
- remove ingested poisons from the lower GI tract
- adjunct in anthelmintic therapy when desirable to flush helminths from GI tract
9
Q
Mineral Oil: Actions
A
- forms a slippery coat on the contents of the intestinal tract
- less H2O is absorbed out of the bolus = less likely to become hard or impacted
10
Q
Mineral Oil: Adverse Effects
A
- diarrhea
- abdominal cramps
- bloating
- perianal irritation
- dizziness
- interference w/ absorption of fat-soluble vitamins
- leakage of stool and straining
11
Q
Magnesium Citrate: Indications
A
- short term relief of constipation
- prevent straining when clinically undesirable
- evacuate the bowel for diagnostic procedures
- remove ingested poisons from lower GI tract
- adjunct in anthelmintic therapy when it is desirable to flush helminths from GI tract
12
Q
Magnesium Citrate: Actions
A
- Increase motility of the GI tract by increasing the fluid in the intestinal contents = enlarges bulk, stimulates local stretch receptors, and activates local activity
13
Q
Magnesium Citrate: Adverse Effects
A
- diarrhea
- abdominal cramps
- bloating
- perianal irritation
- dizziness
14
Q
Castor Oil: Indications
A
- evacuate the bowel for diagnostic procedures
- remove ingested poison from the lower GI tract
- adjunct in anthelmintic therapy when it is desirable to flush helminths from GI tract
15
Q
Castor Oil: Actions
A
- directly stimulates the nerve plexus in the intestinal wall
- causing increased movement and the stimulation of local reflexes