Ch 5 Quiz Flashcards
Explain why DNA is a better template than RNA and why proteins are better catalysts than RNAs
DNA is a more stable replicator, Protein is more versatile and facilitates a broader range of reactions
During the process of replication, compare and contrast the process by which the leading strand and the lagging strand are formed. What is the difference between how the leading strand and the lagging strand are polymerized? How does the direction of polymerization of a new strand relative to the direction of travel of the helicase clue you in to which strand is leading and which is lagging
Leading strand- When the new strand’s 3’ OH is facing the helices unwinding the DNA this is a problem. After the primer starts, the DNA’s polymerase III can carry on for millions of bases until it comes to the end of the DNA strand. Everything in the leading strand happens in 1 go. Goes with the helices
Lagging strand- The growing strand has to face its 3’ OH away from the helixes since the parent strand has its 3’ OH facing toward the helices. Everything in the lagging strand happens multiple times (slower).
the direction of the 3’ end directs you to what strand is leading and what strand is lagging, also helicase runs WITH leading and AWAY from lagging.
figure in chapter 5 of the Primer depicts the “Central Dogma”. Use the words protein, translation, transcription, RNA and DNA to explain the central dogma in words.
the coded genetic information which is hard wired into DNA is transcribed into cassettes composed of mRNA containing the program for protein synthesis
it is when DNA is transcribed into mRNA, which is then translated into proteins
If you were provided with the genetic code (in a table, like the in chapter 5 of the Primer), you should know how to translate any codon into an amino acid. Conversely, if you are given an amino acid, you should be able to write down its codon(s). You should also be able to list all tRNAs that specify a particular amino acid.
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