Ch 47 Drugs For Htn Flashcards

0
Q

Parameters for hypertension in patients without diabetes or chronic kidney disease

A

<90

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1
Q

Parameters for normal bp

A

> 120/80

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2
Q

Parameters for hypertension in patients with diabetes or chronic kidney disease

A

<80

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3
Q

Seven possible lifestyle modifications to reduce blood pressure

A

Weight-loss, sodium restriction, the dash eating plan, alcohol restriction, aerobic exercise, smoking cessation, maintenance of K and Ca intake

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4
Q

What are the first-line drugs used for hypertension

A

Thiazide diuretics

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5
Q

What is the principal adverse effect of thiazides

A

Hypokalemia

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6
Q

Other side effects of using thiazides

A

Dehydration, hyperglycemia, hyperuricemia

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7
Q

How do loop diuretics lower blood pressure

A

By reducing blood volume and promoting vasodilation

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8
Q

How do thiazide diuretics reduce blood pressure

A

Reduction of blood volume and reduction of arterial resistance

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9
Q

Adverse effects of loop diuretics

A

Hypokalemia, dehydration, hyperglycemia and hyperuricemia. Can also cause hearing loss.

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10
Q

Most significant adverse effect of the potassium sparing agents

A

Hyperkalemia

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11
Q

What categories of drugs should potassium sparing diuretics not be used routinely with

A

Ace inhibitors, angiotensin II receptor blockers, or aldosterone antagonist

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12
Q

What are the five subcategories of sympatholytic drugs

A

Beta blockers, Alpha1 blockers, Alpha/beta blockers, centrally acting Alpha2 agonists, and adrenergic neuron blockers

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13
Q

Examples of beta-adrenergic blockers

A

Propanolol, metoprolol (“lol”s)

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14
Q

Examples of thiazide and related diuretics

A

“thiazides” (HCTZ, etc) chlorthalidone

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15
Q

examples of high ceiling (loop) diuretics

A

Furosemide, bumetanide, torsemide

16
Q

Examples of potassium sparing diuretics

A

Amiloride, spironolactone, triamterene

17
Q

Adverse effects of beta blockers

A

Bradycardia, decreased AV conduction, and reduced contractility

18
Q

Beta blockers should not be used by patients with ____

And must be used with care in patients with ____

A

Sick sinus syndrome or second- or third-degree AV block

used with care in patients with heart failure

19
Q

Beta blockers Should be avoided by patients with ___

If they must be given a beta blocker ____ should be employed

A

Should be avoided by patients with asthma; if must be used, a beta-1 selective agent should be employed