Ch 4 & 5: Connective Tissue, Adipose, Cartilage, Bone Q Bank Test 2 Flashcards
Which of the following connective tissue components is located in the ECM but not in the ground substance?
a. Collagen bundles
b. Fibronectin
c. GAGs
d. Hyaluronan
e. Proteoglycans
What cells numerous in loose connective tissue are filled with secretory granules and stain with metachromasia?
a. Macrophages
b. Mast cells
c. Fibrocytes
d. Active fibroblasts
e. Leukocytes
What is the first step of collagen production that occurs after the protein undergoes exocytosis?
a. Cross-linking of collagen fibrils with a short linking collagen
b. Removal of the terminal nonhelical domains by peptidases
c. Hydroxylation of lysine and proline
d. Assembly of subunits to form a larger structure
e. Disulfide bond formation
What is an important part of the role played by macrophages during maintenance and renewal of strong extracellular fibers in connective tissue?
a. Storage for a major energy source needed for ECM maintenance
b. Production of specific collagen subunits
c. A sentinel function against invaders entering the ECM
d. Secretion of matrix metalloproteinases
e. Presentation of antigens important for assembly of collagen bundles
Sulfated GAGs are important constituents of what extracellular structures?
a. Hyaluronan
b. Elastic fibers
c. Type I collagen
d. Proteoglycans
e. Multiadhesive glycoproteins
Which of the following contains binding sites for integrins and is an important part of the ECM in both loose connective tissue and dense irregular connective tissue?
a. Aggrecan
b. Fibronectin
c. Perlecan
d. Fibrillin
e. Most types of collagen
Dense regular connective tissue typically involves which of the following features?
a. Contains mostly synthetically active fibroblasts
b. Contains much ground substance
c. Contains a similar cell population as areolar connective tissue
d. Predominant tissue type in the stroma of most organs
e. Predominantly located in tendons and ligaments
White adipocytes are derived developmentally from what precursor cells?
a. Monocytes
b. Fibroblasts
c. Mesenchymal cells
d. Brown adipocytes
e. Mast cells
What are the relatively large particles formed in the intestinal epithelial cells and rich in ingested lipids?
a. Fatty acids
b. Chylomicrons
c. Glycerols
d. Very-low-density lipoproteins
e. Adipocytes
What substance, released from the adrenal gland and some autonomic neurons, increases lipolytic activity in white adipocytes?
a. Leptin
b. Insulin
c. Norepinephrine
d. Glycogen
e. Triglyceride
What is the most important form of lipid storage in both white and brown adipocytes?
a. Free fatty acids
b. Cholesterol
c. Chylomicrons
d. Glycerol
e. Triglycerides
Important target cells of leptin are found in which organ?
a. Small intestine
b. White adipose tissue
c. Large intestine
d. Hypothalamus
e. Brown adipose tissue
The hormone-sensitive lipase in the cells of adipose tissue acts primarily on what substrate?
a. Glucose
b. Free fatty acids
c. Glycerol
d. Triglycerides
e. Very-low-density lipoproteins
Applied to adipocytes, the term “multilocular” refers to which of the following?
a. The large number of small cytoplasmic lipid droplets
b. The proliferation of the cells in an obese individual
c. The large number of mitochondria in the cells
d. The high density of nerves supplying the tissue
e. The type of mesenchymal cells also present
Fully differentiated white adipocytes are large cells, typically having diameters of approximately what size?
a. 5 μm
b. 10 μm
c. 100 μm
d. 500 μm
e. 1000 μm