Ch. 3B Probability, Statistics, and Pedigrees (Exam 2) Flashcards

Simple Probability & Predicting Genetic Outcomes, Matching Predictions to Observed Outcomes, Tracking & Revealing Patterns of Inheritance in Humans

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1
Q

What is probability?

A

The likelihood of an event occurring

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2
Q

What is the range of probability?

A

0-1

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3
Q

What does a probability of 0 mean?

A

No chance

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4
Q

What does a probability of 1 mean?

A

100% chance

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5
Q

What is the most basic example of probability in genetics?

A

Mendelian ratios

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6
Q

What is the main idea behind independent events?

A

The outcome of Event 1 has no effect on the outcome of Event 2 and so on

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7
Q

What is an example of an independent event?

A

A coin toss b/c one toss will not affect the outcome of other tosses

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8
Q

Which math law corresponds to independent events?

A

Product law

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9
Q

What is another name for the product law?

A

Multiplication rule

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10
Q

What is the main idea behind mutually exclusive events?

A

They do not occur at the same time

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11
Q

What keywords can help identify a mutually exclusive event?

A

Either/or

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12
Q

Which math law corresponds to mutually exclusive events?

A

Sum law

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13
Q

What is another name for the sum law?

A

Addition rule

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14
Q

What is the main idea behind conditional probability?

A

The probability of a particular outcome depends on another outcome or given condition

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15
Q

What is the formula for conditional probability?

A

Pc = Pa / Pb

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16
Q

What does each variable for conditional probability stand for?

A
Pc = conditional probability
Pa = probability of an event/interest
Pb = probability of a given conditional event
17
Q

What keyword may help possibly identify conditional probability scenarios?

A

Given

18
Q

What does binomial theorem calculate?

A

The outcome of repeated trials with only 2 outcomes

19
Q

When solving binomial distribution the long way, what are the 2 main steps involved?

A

Step 1) Product law

Step 2) Sum law

20
Q

What does the product law step of binomial distribution detail?

A

Calculating the product of independent events to get an initial probability

21
Q

What does the sum law step of binomial distribution detail?

A

Finding the # of possible combinations and adding the initial probability from the previous step based on the # of combinations i.e. 3 combinations = adding the initial probability to itself 3 times

22
Q

What popular algebraic concept can be used to solve binomial distribution? List this formula too.

A

Pascal’s triangle - (a +b)^n = 1

23
Q

What is the main binomial distribution formula that will most likely be used on the exam?

A

((n!) / (s! * t!)) * ((a^s) * (b^t))

24
Q

What does the binomial distribution variable “n” stand for?

A

n = # of trials/repeats

25
Q

What does the binomial distribution variable “s” stand for?

A

s = # of 1st outcome

26
Q

What does the binomial distribution variable “t” stand for?

A

t = # of 2nd outcome

27
Q

What does the binomial distribution variable “a” stand for?

A

a = probability of 1st outcome

28
Q

What does the binomial distribution variable “b” stand for?

A

b = probability of 2nd outcome

29
Q

When is a deviation in data more likely to occur?

A

When there is a small sample size

30
Q

What is the general definition of the null hypothesis?

A

The assumption that there is no difference or deviation

31
Q

What 2 assumptions does the null hypothesis make about differences in measured & predicted values?

A

1) Data/ratios that agree with our expectations show no difference between measured & predicted values
2) Any differences between measured & predicted values can be attributed to chance

32
Q

What is the overall goal of the null hypothesis?

A

To reject or accept the null hypothesis

33
Q

What does it mean to reject the null hypothesis?

A

Differences found are not due to chance, so you should re-examine your data/assumptions

34
Q

What does it mean to accept the null hypothesis?

A

Differences found between observed & expected outcomes are due to chance

35
Q

What does a chi-square analysis determine about your observed data?

A

Determines how well measured/observed data fits the accepted data

36
Q

How do the results of a chi-square analysis relate to the null hypothesis?

A

The chi-square analysis tells if your results reject or accept the null hypothesis