Ch 38 Agents to control blood glucose levels Flashcards
Adiponectin
Or moans produced by adipocytes that acts to increase insulin sensitivity, decrease the release of glucose from liver, and protect the blood vessels from inflammatory changes
Diabetes, Mellitus 
A metabolic disorder characterized by high blood glucose levels, and altered metabolism of proteins and fats; associated with thickening of the basement membrane, leading to numerous complications
Endocannabioid receptors
Receptors found in the adipose tissue, muscles, liver, satiety Center, and gastrointestinal tract that are part of a signaling system within the body to keep the body in a state of energy gain
Dipeptidyl peptidese-4 DPP-4
Enzyme that quickly metabolizes Glucagon like polypeptide one
Glucagon like polypeptide one GLP 1
A polypeptide produced in the G.I. tract in response to carbohydrates that increases insulin release, decreases, glucagon release, slows, G.I. emptying, and stimulates the satiety center in the the brain
Glycogen 
Storage form of glucose; can be broken down for rapid glucose level increases during times of stress
Glycosuria
Presence of glucose in the urine
Glycosylated hemoglobin
A blood glucose marker that provides a three month average of blood glucose levels
Hyper glycemia
Elevated blood glucose levels, leading to multiple signs and symptoms and abnormal metabolic pathways
Hypoglycemia
Lower than normal blood sugar; often results from imbalance between insulin or oral agents and the patient’s eating, activity, and stress; symptoms of hypoglycemia may be seen if blood sugar is 70 mg/dL or lower 
Incretins
Peptides that are produced in the G.I. tract in response to food that help moderate insulin and glucagon activity
Insulin
Hormone produced by the beta cells in the pancreas; stimulate insulin receptor sites to move glucose into the cells; promotes storage of fat and glucose in the body
Ketosis
Breakdown of fats for energy, resulting in an increase in ketones to be excreted from the body
Polydipsia
Increased thirst; scene and diabetes, and lots of fluid and increase tonicity of the blood lead the hypothalamic thirst center to make the patient feel thirsty
Polyphagia
Increased hunger; sign of diabetes, when cells cannot use glucose for energy and feel that they are starving, causing hunger