Ch 32 prepu Flashcards

1
Q

The pharmacology instructor is discussing age-related susceptibility to adverse effects of cholinergic drugs. Which statement could the instructor make to accurately describe the influence of age?

“Older adults are at higher risk for adverse effects because they receive higher doses.”

“Physiologic changes resulting from the normal aging process place older adults at higher risk for adverse effects.”

“Children are more susceptible to adverse effects because they receive more potent drugs than adults.”

“All age groups are equally susceptible to adverse effects.”

A

“Physiologic changes resulting from the normal aging process place older adults at higher risk for adverse effects.”

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2
Q

The nurse is caring for a client who is receiving neostigmine for the treatment of myasthenia gravis. The nurse is aware that a potential complication of the treatment is cholinergic crisis, which is characterized by which event?

hypertension and respiratory failure

excessive stimulation of the sympathetic nervous system

stronger skeletal muscle contractions

excessive stimulation of the parasympathetic nervous system

A

excessive stimulation of the parasympathetic nervous system

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3
Q

The nursing instructor is teaching students about Alzheimer’s disease. The instructor informs the students that clients with this illness experience problems with memory and thinking. The reason that this happens is which?

Regeneration of cholinergic pathways

Lack of neural destruction

Increased level of acetylcholine

Degeneration of cholinergic pathways

A

Degeneration of cholinergic pathways

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4
Q

Which agent would be used to counteract a severe reaction occurring with the use of neostigmine?

Phentolamine

Atropine

Edrophonium

Naloxone

A

Atropine

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5
Q

Jack Thomas is a 45-year-old automobile mechanic with a history of throat cancer. Jack has just undergone radical neck resection. As a result of the surgery, Jack suffers from xerostomia, a dry mouth condition. He is prescribed pilocarpine therapy. What advice should you give Jack regarding the drug therapy?

Jack should be encouraged to consume more caffeine-containing beverages because that cuts the craving for smoking.

Jack should be instructed about the Ocusert system.

Jack should be near a urinal at all times.

Jack should be cautioned about blurred vision and its hazards.

A

Jack should be cautioned about blurred vision and its hazards.

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6
Q

A nurse is caring for a 49-year-old client who has been taking bethanechol for treatment of neurogenic bladder. After one week, the client develops sweating, heavy salivation, and bronchospasm. What would the nurse suspect is happening with this client?

Anaphylactic reaction

Cholinergic crisis

Pulmonary edema

Myasthenic crisis

A

Cholinergic crisis

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7
Q

The nurse is caring for a client who has been diagnosed with myasthenia gravis. To ensure client safety, the nurse reviews treatment for myasthenic crisis, which requires what intervention?

withdrawal of anticholinesterase drugs

additional anticholinesterase inhibitors

withdrawal of immunoglobulin drugs

a decrease in glucocorticoid therapy

A

additional anticholinesterase inhibitors

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8
Q

The client is receiving Bethanechol for bladder atony. What assessment findings indicate the effect of this medication?

Increased hemoglobin

Increased red blood cell (RBC) count

Increased blood pressure

Increased urinary output

A

Increased urinary output

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9
Q

A nurse caring for a client receiving bethanechol for urinary retention should advise the client that voiding usually occurs how long after oral administration?

30 to 90 minutes

2 to 4 hours

12 to 24 hours

5 to 15 minutes

A

30 to 90 minutes

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10
Q

A 78-year-old man is admitted to the emergency department (ED) with bradycardia resulting from overdose of donepezil. The nurse knows that the ED is likely to order which medication?

propranolol

atropine

bethanechol

pseudoephedrine

A

atropine

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11
Q

A patient with dementia of Alzheimer’s disease is prescribed rivastigmine by the primary health care provider. Which is the correct method of administering rivastigmine to the patient?

Intravenously

Orally

Subcutaneously

Intramuscularly

A

Orally

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12
Q

A client experiences an overdose of a cholinergic drug. Which medication would the nurse anticipate that the client will receive as a reversal agent?

Epinephrine

Atropine

Dopamine

Norepinephrine

A

Atropine

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13
Q

A client with Alzheimer’s disease is being treated with the medication Exelon. The nurse knows that this drug is also used to treat which disorder?

hepatic disease

Parkinson’s disease

seizures

asthma

A

Parkinson’s disease

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14
Q

Which medication would the nurse expect to administer orally once a day to a client with Alzheimer disease (AD)?

Donepezil

Memantine

Rivastigmine

Galantamine

A

Donepezil

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15
Q

A 70-year-old female patient has just been diagnosed with Alzheimer’s disease. What cholinergic drug is used for the treatment of Alzheimer’s disease?

Bethanechol (Duvoid)

Edrophonium (Tensilon)

Donepezil (Aricept)

Neostigmine (Prostigmine)

A

Donepezil (Aricept)

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16
Q

The nurse is developing a teaching plan for an outpatient receiving cholinergic drugs. What should be the role of the nurse when developing a teaching plan?

Review the purpose of the drug therapy with the patient and family.

Review the patient’s previous history of disorders.

Suggest the patient adapt a self blood pressure measurement habit.

Suggest the patient avoid fiber-rich food during therapy.

A

Review the purpose of the drug therapy with the patient and family.

17
Q

How do direct-acting cholinergic drugs affect the bladder? (Select all that apply.)

Relaxation of the sphincter

Increased bladder capacity

Reduction in UTIs

Ability to better empty the bladder

Increased tone and contractility

A

Increased tone and contractility

Relaxation of the sphincter

Ability to better empty the bladder

18
Q

A client has been receiving bethanechol for 1 week. One hour after the dose is administered, the client develops sweating, flushing, abdominal cramps, and nausea. The nurse prepares to intervene for what condition?

Anaphylactic reaction

Cholinergic overdose

Myasthenic crisis

Pulmonary edema

A

Cholinergic overdose

19
Q

The nurse is providing information about how to care for clients during a bioterrorism attack. The nurse knows that which drug will be administered in the case of a sarin attack?

Donepezil

Bethanechol

Neostigmine

Atropine

A

Atropine

20
Q

Which best reflects the action of direct acting cholinergic agonists?

They prevent the breakdown of acetylcholine.

They undergo chemical reaction with acetylcholinesterase.

They mimic the action of the sympathetic nervous system.

They occupy receptor sites for acetylcholine.

A

They occupy receptor sites for acetylcholine.

21
Q

A female patient has been administered donepezil HCL for dementia. The patient has informed the nurse that she has also been taking nonsteroidal anti-inflammatory drugs. Which interaction should the nurse monitor for in this patient?

Decreased effectiveness of anticholinergics

Increased risk of GI bleeding

Decrease GI absorption of the drug

Increased risk of theophylline toxicity

A
22
Q

A client is prescribed donepezil. The nurse would expect to administer this drug at which frequency?

Once a day

Four times a day

Twice a day

Three times a day

A

Once a day

23
Q

A female client is taking cholinergic medication to control bladder retention. She presents to the emergency department with confusion, shortness of breath, and an apical pulse of 42 beats per minute and irregular. What action would the nurse expect the health care provider to take?

Increase the cholinergic medication to increase oxygenation to the heart through vasodilation.

Decrease the cholinergic medication to alleviate the symptom of confusion.

Discontinue the cholinergic medication secondary to the diagnosis of bradycardia.

Increase the cholinergic medication to increase cardiac contractility.

A

Discontinue the cholinergic medication secondary to the diagnosis of bradycardia.

24
Q

A client being treated for myasthenia gravis is receiving neostigmine. When the client’s pulse drops to 50 after the administration, which medication should be administered to treat the bradycardia?

Propranolol

Pseudoephedrine

Atropine

Bethanechol

A

Atropine

25
Q

A military nurse is part of a team reviewing the appropriate response to chemical weapons attacks, including sarin, tabun, and soman. When reviewing the physiology of a response to such drugs, the nurse should identify what goal of treatment?

Restore GABA function

Restore anticholinesterase function

Restore appropriate serotonin reuptake

Restore dopamine function

A

Restore anticholinesterase function

26
Q

A patient with dementia of Alzheimer’s disease is administered donepezil HCL. What are the actions associated with cholinesterase inhibitors?

Increase in the level of adenosine tri-phosphate in the blood

Increase in the level of cholinesterase in the blood

Decrease in the level of neurotoxins in the brain

Increase in the level of acetylcholine in CNS

A

Increase in the level of acetylcholine in CNS

27
Q

A group of students are reviewing the drugs that are available for treating Alzheimer’s disease. The students demonstrate understanding of the information when they identify which drug as appropriate for treatment?

Pyridostigmine

Rivastigmine

Cevimeline

Edrophonium

A

Rivastigmine

28
Q

The pharmacology instructor is discussing the drug therapy for Alzheimer’s disease with a group of nursing students and states that indirect-acting cholinergic drugs do what to improve symptoms?

Cause vasodilation of the cerebral arteries

Improve medication absorption through the blood–brain barrier

Improve anticholinergic neurotransmission to the brain

Improve cholinergic neurotransmission to the brain

A

Improve cholinergic neurotransmission to the brain