Ch 32 Cholinergic

Question 1

T/F: A woman with myasthenia gravis who is taking pyridostigmine (Mestinon) should be cautioned against becoming pregnant because the uterus may be stimulated and labor induced, resulting in a preterm birth.

Answer 1

True

Question 2

T/F: The treatment for nerve gas exposure includes the use of pralidoxime (Protopam Chloride), which is the antidote for irreversible acetylcholinesterase-inhibiting drugs, and atropine, which temporarily blocks cholinergic activity.

Answer 2

True

Question 3

T/F: The use of direct-acting cholinergic drugs is limited to primarily ophthalmic agents because of their profound negative systemic effects.

Answer 3

True

Question 4

T/F: Edrophonium (Enlon) is used as a diagnostic agent to distinguish between a myasthenic crisis and a cholinergic crisis.

Answer 4

True

Question 5

_____________ disease is a progressive disorder involving neural degeneration in the cortex that causes profound loss of memory and affects a person’s ability to complete daily activities.

Answer 5

Alzheimer’s

Question 6

Chemicals that act at the same site as the neurotransmitter acetylcholine (ACh) are called ____________ drugs.

Answer 6

cholinergic

Question 7

___________ is approved for use in children older than 8 years of age for the treatment of neurogenic bladder.

Answer 7

Bethanechol

Question 8

____________ is a chronic muscular disease caused by a defect in neuromuscular transmission.

Answer 8

Myasthenia Gravis

Question 9

T/F: Galantamine (Razadyne) is a cholinergic drug that is used to stop the progression of Alzheimer’s disease.

Answer 9

False

Question 10

An example of an irreversible acetylcholinesterase inhibitor that leads to toxic accumulations of ACh at the cholinergic receptor sites and can cause muscle paralysis is ___________________.

Answer 10

nerve gas