Ch 3.1

Question 1

What are two common mistakes about database information

Answer 1

• repitition of into doesn’t mean independent info so not validation
• share a lot of into but not all contain the same information

Question 2

Termes can be used to search databases. How can yay narrow down your searches?

Answer 2

-boolean nonnectors (AND, OR, NOT), can also narrow down field.

Question 3

What are some components of a gene bank entry?

Answer 3

Reference to who submitted, what is an accession number???? (letters and numbers that make an entry 28min NB!)

Question 4

How do we learn from comparing genomes/genes?

Answer 4

-through uniqueness (genes groups like metabolic capacity to colonize skin pimple bacteria, sugar uptake genes in gut bactera), similarities and differences

Question 5

What makes some Ecoli strains pathogenic?

Answer 5

• horizontal transfer
• not widespread in genome, just regions that are prone to acquire the transfer go genes
• DNa islands which are hotshots for the horizontal transfer.

Question 6

Prokaryotes 6

Answer 6

• Larger genome=more genes
• little intra/intragenic space
• genome growth by duplications + horizontal transfer
• limited variation in genome sizes
• growth of genomes limited by deletion bias
• correlation with/btwn genome size and ecological/enviormental challenges

Question 7

Eukaryotes 6

Answer 7

• Larger genomes no= more genes
• increases in intra/intragenic spaces
• genome growth by duplications
• large variation in genome sizes
• specialization by regulation of gene expression—>larger intragenic spaces, more transcription factors
• specialize by using alternative splicing, one gene—many products