Ch. 30 & 31 Flashcards
Name major structures in the hematopoietic system.
Bone marrow, Blood, Lymphatic system.
What is a type of anemia in which erythrocytes become sickle or crescent shaped when oxygen supply in the blood is inadequate?
Sickle cell
What blood type is considered a universal recipient?
AB blood type
Foreign material, their numbers increase in allergies, some dermatological disorders, and parasitic infections
Eosinophils
Is the liquid,or serum, portion of blood. It consists of 90% water and 10% proteins
Plasma
What signs do you typically have when you have leukopenia?
Fever, sore throat, chills
Define leukocytosis and leukopenia
Leukocytosis: increased number of leukocytes
Leukopenia: decreased number of leukocytes
What does the lymphatic system consist of?
Thymus gland, spleen, and a network of sympathetic vessels, lymph nodes, and lymph.
What is acute chest syndrome?
A type of pneumonia triggered by decreased hemoglobin and infiltrates in the lungs.
Any malignant blood disorder in which proliferation of luekocytes, usually in an immature form, is unregulated
Luekemia
What term means opening a vein to withdraw blood?
Phlebotomy
Hemoglobin levels for someone with sickle cell disease
7-10 g/dL
Signs and symptoms of Hypovolemic anemia
changes in vital signs noted, signs of shock with severe loss
The manufacture, and development of blood cells
Hematopoiesis
The red color of blood is the result of
Hemoglobin
Found in the ribs, sternum, skull, clavicles, vertebrae, proximal ends of the long bones and iliac crest
Red marrow
What are the hallmarks of luekemia?
Infections, fatigue from anemia, and easy bruising
Blood consists of cells suspended in a fluid called
Plasma
Normal range of hemoglobin:
12.0 to 17.4
A term that refers to a deficiency of either erythrocytes or hemoglobin.
Anemia
What does the lymphatic system include?
Thymus gland, spleen, and a network of lymphatic vessels, lymph nodes, and lymph.
Is a hormone released by the kidneys
Erythropoietin
The term ____ refers to conditions in which a component that is necessary to control bleeding.
Coagulopathy
small hemorrhages in the skin, mucous membranes, or subcutaneous tissues.
Purpura
How does thrombocytopenia occur?
When the platelets manufactured by the bone marrow are decreased or platelet destruction by the spleen in increased.
Term that refers to a deficiency of either erythrocytes or hemoglobin
Anemia
Leukocytosis
An increased number of leukocytes above normal limits
The normal number of erythrocytes varies with age, gender, and altitude and ranges between ____- and ____
3.6 and 5.4 million/mm
Define erythrocytes:
RBCs; transport oxygen and carbon dioxide
List the 4 blood groups and which one can everyone receive?
A, B, AB, O and everyone can receive O negative.
What is the most abundant protein in plasma
Albumin
What is the first symptom of multiple myeloma?
The first symptom usually is vague pain in the pelvis, spine, or ribs.
Normal lab value of platelets
150,000-450,000
Treatment for sickle cell disease
supportive, blood transfusions, medications to treat symptoms.
The basic nutritional component of heme in hemoglobin
Iron
What are signs for Leukopenia
Fever, sore throat, chills
The building block of hemoglobin and the enzymes involved in red blood cell production
Protein
Hemophilia is inherited from..
mother to son
Thrombocytopenia
A lower-than-normal number of platelets or thrombocytes
Define purpura
Small hemorrhages in the skin
What is fibrinogen’s function
It plays a key role in forming blood clots
Is a term that refers to a deficiency of either erythrocytes or hemoglobin
Anemia
refers to conditions in which numbers of all marrow produced blood cells are reduced
pancytopenia
Treatment for Iron-deficiency
Determine the cause and eliminate it. Correct diet, add supplements
Define osteoclasts
Cells hat breakdown and remove bone cells
What is the most common type of hemophilia?
Hemophilia A, and it results from a deficiency of factor VIII
Most common cause of agranulocytosis is toxicity from drugs such as..
sulfonamides, chloramphenicol, antineoplastics, and some psychotropic medications.
What is sickle cell disease
A type of anemia in which erythrocytes become sickle - crescent- shaped when oxygen supply in the blood is inadequate
Blood dyscrasias
Abnormalities in numbers and types of blood cells, and coagulopathies,bleeding disorders that involve platelets or clotting factors
Define leukemia
Any malignant blood disorder in which proliferation of leukocytes is unregulated
What are the signs and symptoms of hypovolemic anemia?
Extreme pallor, tachycardia, hypotension, reduced urine output, and altered consciousness
Hemolytic
Generic term for anemia when caused by other conditions, such as malaria
What are the major groups of thalassemias?
Alpha-thalassemias and beta-thalassemias
____ anemia is a consequence of blood loss
Hypovolemic anemia
Thrombocytopenia
Lower than normal number of platelets or thrombocytes
enlargement of the spleen
splenomegaly
Signs and symptoms of Sickle cell disease
Family history, cells clog, reducing blood flow, causes severe pain, ischemia, fever, possible tissue infarction
Pancytopenia
Conditions in which numbers of all marrow-produced blood cells are reduced.
What is the largest lymphatic structure
The spleen
Define chelation therapy
A process in which heavy metals such as iron are pharmacological removed from the blood
If an older adult is anemic, blood loss from the..
GI or genitourinary tract is suspected.