Ch 3 Prenatal Development Flashcards

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1
Q

Embryology

A

Study of prenatal development

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2
Q

Gametes

A

Sex cells

New organism is produced when they unite and fuse together

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3
Q

Male gamete

A

Sperm

Produced in testes

Survive for several days

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4
Q

Female gamete

A

Secondary oocytes (potentially mature ova)

Produced from ovaries

Survive several hours

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5
Q

Zygote

A

Cell resulting from union and fusion of gametes

Fertilized egg

Contains chromosomes (dna) from both parents

From repeated mitotic cell division it develops into new organism (cleavage);

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6
Q

Gamete differ from other Somites body cells, they contain

A

Haploid chromosome number
“N”

In humans n=23
A single set of chromosomes

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7
Q

Diploid chromosome number

A

2n

In nucleus of somatic cells

In humans this number is 46 (2 sets of 23)

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8
Q

Meiosis

A

Process of cell division in which diploid cells in testes and ovaries are converted into haploid gametes

End result is 4 cells

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9
Q

Meiosis I

Meiosis II

A

Gamete splits and goes to separate cells

Splits into 4
-not identical
-each separate
-law of probability of combo of genes

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10
Q

Down syndrome

A

Meiosis malfunction

Trisomy 21

Congenital defects that could affect mouth and teeth

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11
Q

Prenatal development consists of ___ lunar months and is divided into 3 successive periods. Which are?

A

10

1)Preimplantation
2)Embryonic
3)Fetal Period

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12
Q

Preimplantation period

A

Wk 1

Fertilized egg (zygote) niche into wall of endometrium

Zygote develops into morula after mitosis

Morula into blastocyst

7-10 days blastocyst implants and consists of
-trophoblast
-embryoblast

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13
Q

Morula

A

Solid ball of cells

Mitosis ongoing and fluid secretions

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14
Q

Blastocyst

A

Vesicle developed from morula

Undergoes implantation after 7-10 days and turns into trophoblast and embryoblast

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15
Q

Trophoblast

A

Layer of peripheral cells

Develops into placenta

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16
Q

Embryoblast

A

Small inner mass of embryonic cells

Develops to embryo

17
Q

Embryonic period

A

Wk 2-8

First 3 weeks=proliferation, migration and some differentiation

Following 4 weeks=differentiation of all major external and internal structures

Vulnerable period for the embryo

18
Q

Physiological processes occurring during Embryonic period (5)

A
  1. Induction
  2. Proliferation
  3. Differentiation
  4. Morphogenesis
  5. Maturation
19
Q

Induction

A

Embryonic period

Group of cells induce other groups of cells to take different path

20
Q

Proliferation

A

Controlled cellular growth, by genes

21
Q

Differentiation

A

Taking on different structure to take on diff function

22
Q

Morphogenesis

A

Development of specific tissue structure and shape

23
Q

Maturation

A

Attaining adult size and function

Most predominant

24
Q

2nd week of development

A

Creation of bilaminar embryonic disc

-flattened circular plate of bilateral cells
Consists of epiblast layer and hypoblast layer

25
Q

Epiblast layer

A

Composed of high columnar cells and faces amniotic cavity

26
Q

Hypoblast layer

A

Small cuboidal cells and faces yolk sac

27
Q

Major events of wk 3

A

Forming of primitive streak

Migration of some cells of epiblast to locate in between epi and hypo to form mesenchyme

Bi to tri disc (Ectoderm, Mesoderm, endoderm)

Oropharyngeal membrane
Or
Buccalpharyngeal membrane
Cloacal membrane

Development of nervous system
Diff. Neuroectoderm cells of neural plate
Forming of neural groove, groove to folds, folds fuse to tube

Neural crest cells

28
Q

Major events wk 4

A

Embryonic folding of disc into embryo and tissue in proper positions for further development

Ectoderm outside
Middle mesoderm
Inside endoderm

All organs present, membranes developed

Placenta developed 3rd month

29
Q

Fetal period

A

9 wks to birth

Maturation of existing structures as embryo enlarges to fetus

(Last 2 trimesters)

30
Q

Spindobifida

A

At wk 3 neural folds do not fuse properly to form neural tube

31
Q

Primitive streak

A

Furrowed, rod shaped thickening that causes disc to have symmetry

Right and left half

32
Q

Mesenchyme

A

Embryonic connective tissue

33
Q

Ectoderm

A

Wk 3

Forms from epiblast

All epithelium and nervous system comes from

34
Q

Mesoderm

A

Wk 3 embryonic

Somites

Everything in between Epithelium of skin and digestive tract

35
Q

Endoderm

A

Digestive tract develops from this

Formed from hypoblast

36
Q

Buccopharyngeal membrane
or
Oropharyngeal “ “

Cloacal membrane

A

@ cephalic end of disc, beginning of digestive tract

@ caudal end , end of dig. Tract

Both consist only of ectoderm and endoderm (fused)

37
Q

Neural crest cells

A

Differentiate from neuroectoderm (taking on different structure to take on different function)

Will develop head and neck

38
Q

Somites

A

Form end of wk 3

Mesoderm divides on each side of tube into 38 paired cuboidal segments

39
Q

Implantation

A

Blastocyst embedded in endometrium, the innermost lining of the uterus on its back wall