Ch 3 Factors Influencing Health Flashcards
Biologic and genetic determinants
Physiologic factors that are inherent in individuals, and some cannot be changed.
Biologic and genetic determinants examples
Age, body structure, and body function
Arthrometric Measurement (Measured Body Structure) examples
Height Weight Body mass index (BMI) Waist-to-hip ratio Bone density
Organic bodily processes examples
Biochemical function Blood pressure Movement and balance Nutritional status Respiratory function Sensory function Strength and robustness Fitness
Genetic Vulnerability
Risk for disease expression based on genotype, is a determinant of health involuntarily passed from biologic parents to their offspring
Epigenetics
A branch of genetics that studies changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself (i.e., heritable changes in gene activity that are not caused by changes in the DNA sequence)
Genetic Susceptibility
Individuals with a genetic susceptibility, or genetic predisposition, may not be born with a disease but may be at high risk for acquiring it
Clinical genetics
A branch of genetics that studies inherited disorders and investigates the possible factors that may influence the occurrence of pathologic conditions. It does not specifically refer to the risk for disease expression passed on involuntarily from biologic parents to offspring
Which patient factors are considered biologic determinants of health?
Age, bone density, respiratory function
Which condition is an example of a chromosomal disorder?
Down Syndrome
Examples of Single gene disorders:
Cystic fibrosis Phenylketonuria Sickle cell anemia Hemophilia A Familial hypercholesterolemia Huntington disease
The SIX basic patterns of single-gene inheritance:
autosomal dominant autosomal recessive X-linked dominant X-linked recessive Y-linked inheritance maternal (mitochondrial) inheritance
In chromosomal disorders, the defect is due to an excess or lack of the genes contained in a whole chromosome or chromosome segment. Examples of chromosomal disorders include:
Down syndrome
Klinefelter syndrome
Turner syndrome
Multifactorial disorders: Common diseases involve interactions of several genes and the environment. Examples of multifactorial disorders include:
Cancer
Coronary heart disease
Hypertension
Stroke
Which population has the greatest risk for opportunistic infections?
Older adults have the greatest risk for opportunistic infections caused by harmless organisms that become pathogenic; older adults have decreased immune system function as a result of the aging process.