Ch 26 - neuroplasticity Flashcards
what is plasticity?
ability to change
what is neuroplasticity?
any observable change in neuron structure or function
why are behavioral measurement and measurement of plasticity interdependent?
because behavioral changes are mediated by neural plasticity indirectly.
what are the structural factors for individual neurons?
dendritic arbor, spine density, synapse number, synpase size, axonal arbor, receptor density
functional factors for individual neurons?
EPSPs, neural activity, intrinsic excitability
structural factors for populations of neurons
structure thickness, gray matter density
functional factors for populations of neurons
sensory map, motor map, EEG, fMRI, PET, MEG, MEPs, EPSPs
what are common measures of neuroplasticity?
individual neurons - changes in morphological characteristics
populations of neurons - removing a defined piece of CNS, volume or thickness of a particular area, changes in synpatic potential
spinal cord segments - measure changes in rate depression following injury
what is the difference between recovery and compensation?
recovery is restoring function in residual neural tissue that was initially lost due to injury or disease.
compensation is when residual neural tissue takes over function of tissue lost due to injury or disease
how does plasticity reflect changes in neural circuitry?
multiple overlapping mechanisms are operating together over time to impart changes in neural circuitry that can both occur in seconds or over years. neural plasticity occurs continuously. its responsible for our ability to learn and occurs in response to a variety of internal and external signals.
provide a few examples of structural and functional changes that occur due to neural plasiticity.
increased strength of existing synapses; addition of new synapses; motor map reorganization
how does experience-dependent neural plasticity support learning?
use it or lose it
use it and improve it
specificity; repetition matters; intensity matters; time maters; salience matters; age matters; transference; interference
how can neuroplasticity be applied to neurorehabilitation?
the capacity to acquire, retain and use novel behaviors is maintained throughout life and these capacities are the same ones used to relearn abilities lost after injury