Ch 24: Infections and Infestations, Primary Neoplasms

Question 1

Superficial bacterial infection of the skin that occurs mostly in children. Characteristic honey-colored crusted erosions on hands, face, extremities

Answer 1

Impetigo

Question 2

Bacterial (usually staph or strep) invasion of superficial skin forming necrotizing ulcerated lesion with neutrophils present

Answer 2

Ecthyma

Question 3

Fungi that infect keratinized epithelium by producing keratinases

Answer 3

Dermatophytes

Question 4

Benign neoplasms of melanocytes within the epidermis and/or dermis

Answer 4

Nevi

Question 5

Nevi that do not follow a typical pattern of growth and differentiation

Answer 5

Dysplastic nevi

Question 6

Neoplasm of melanocytes

Answer 6

Malignant melanoma

Question 7

Melanomas are dependent to some extent on mutations in this gene

Answer 7

B-RAF

Question 8

Melanoma growth phase characterized by horizontal growth along the epidermis and superficial dermis with a low risk of metastasis

Answer 8

Radial growth phase

Question 9

Melanoma growth phase marked by growth into the deep dermis and associated with increased risk of metastasis. Most important prognostic factor in predicting metastasis

Answer 9

Vertical growth phase

Question 10

Melanoma that bypasses the normal tumor progression and manifests malignant qualities in the initial lesion. It’s usually in vertical growth phase when initially observed

Answer 10

Nodular melanoma

Question 11

A large, pigmented macule due to chronic ultraviolet light exposure that occurs on sun-damaged skin of fair-skinned, usually elderly whites who have no history of acute sunburn injury, but often worked outdoors

Answer 11

Lentigo Maligna Melanoma (also known as Hutchinson melanotic freckle)