Ch 22 - Anticoagulants and Antiplatelet agents Flashcards
1
Q
What is thrombosis?
A
- the formation of unwanted clot within a blood vessel
- the most common abnormality of hemostais
2
Q
Thrombotic disorders include:
A
- acute myocardial infarction (MI)
- deep vein thrombosis (DVT)
- pulmonary embolism (PE)
- acute ischemic stroke
3
Q
how doe we treat thrombotic disorders?
A
using anticoagulants and fibrinolytics
4
Q
Disorders involving the failure of hemostasis:
A
- hemophilia, which is treated with transfusion of recombinant factor VIII
- vitamin K deficiency, which is treated with vitamin K supplementation
5
Q
What is a thrombus?
A
A clot that adheres to a vessel wall
6
Q
What is an embolus?
A
an intravascular clot that floats in the blood
7
Q
Where does most arterial thrombosis occur?
A
medium-sized vessels
8
Q
What does the arterial thrombosis usually consist of?
A
a platelet-rich clot
9
Q
What triggers venous thrombosis?
A
- blood stasis
- inappropriate activation of the coagulation cascade
10
Q
What does the venous thrombosis consist of?
A
it is rich in fibrin, with fewer platelets than are observed with arterial clots.
