Ch. 22 Flashcards
What is the Hardy Weinberg Law?
a model for allele and genotype frequencies
- prediction 1: allelic frequencies of a population do not change
- the genotypic frequencies stabilize
assumptions: large, randomly mating, not affecting by mutation
Hardy Weinberg terms
p2: homozygous dominant allele pair frequency (dominant X dominant frequency, 0.5 X 0.5)
q2: homozygous recessive allele pair frequency (recessive X recessive, 0.5 X 0.5)
2pq: heterozygous allele frequency
they all add up to ONE, total frequency
calculating allelic frequencies
frequency = #copies of the allele/#copies of all alleles at the locus in a population
f(A) = p = number of big As/total number of allele
lower than genotypic frequencies
P + Q = 1
homozygosity by descent
inbreeding causes alleles to be identical by descent
comes from a common ancestor
heterozygosity by state
not from a common ancestor, not caused by inbreeding
What affects the genotypic frequencies of a population?
nonrandom mating
mutations
migration
nonrandom mating
- positive assortative mating
- negative assortative mating
- inbreeding v. outcrossing
- inbreeding coefficient
- inbreeding depression
inbreeding v outcrossing
inbreeding: same lineage
outcrossing: no shared common ancestor
negative and positive assortative mating
tendency of like/unalike individuals to mate
inbreeding depression
result of self fertilizing
less diversity, weakening the individuals (no inbreeding, creating hybrids, is the opposite), no genetic growth in population
what happens when no mutations isn’t met for Hardy Weinberg?
- changes the allelic frequencies
- reaches equilibrium of allelic frequencies
- recurrent mutations change allelic frequencies (forward and reverse mutations –> increased stability in equilibrium
what to Hardy Weinberg when the population migrates?
- changes allelic frequencies
- more change will occur in migration if higher frequencies of alleles