Ch. 2 Principles of Drug Action Flashcards
_________________ is the study of the disposition of drugs in the human body: their absorption, distribution, metabolism, and excretion.
A. Pharmacokinetics
B. Pharmacodynamics
C. Physiology
D. Pharmacology
A. Pharmacokinetics
The extent to which a drug completes the processes of absorption, distribution, metabolism, and excretion depends
on its ability to cross the cell membrane and on
A. How many layers of cells there are
B. How quickly it can do so
C. How strong a dose was given
D. How much food was in the patient’s stomach at the time the drug was given
B. How quickly it can do so
The main actions of drugs in the body are what?
A. Metabolizing, stimulating, maintaining, and destroying cells
B. Absorbing, depressing, enhancing, and stimulating
C. Depressing, destroying cells, stimulating, and replacing substances
D. Distributing, metabolizing, replacing, and excreting
C. Depressing, destroying cells, stimulating, and replacing substances
Each drug interacts in a different way with normal body processes. These interactions are determined by
A. The size and shape of drug molecules and how easily they dissolve in water or fat
B. The pH balance of drugs and cells
C. The electrical charges of molecules
D. All of these
D. All of these
_________________ is the passage of a drug from the site of administration into the bloodstream.
A. Metabolism
B. Absorption
C. Dissipation
D. Distribution
B. Absorption
The transportation of a drug from the bloodstream to the body’s tissues and intended site of action is known as
A. Metabolism
B. Movement
C. Absorption
D. Distribution
D. Distribution
_________________ is a series of chemical reactions that inactivate a drug by converting it to a water-soluble compound that can be excreted.
A. Metabolism
B. Distribution
C. Digestion
D. Excretion
A. Metabolism
Drugs are removed from the body in the same way as ordinary waste products, through?
A. Sweating
B. Metabolism
C. Excretion
D. Distribution
C. Excretion
Which of the following factors affect drug action?
A. Age, sex, and diet
B. Genetic makeup
C. Pathological condition
D. All of these
D. All of these
A patient’s ______________ is an important factor contributing to the effectiveness of drug therapy because a positive attitude can
play a role in successful treatment.
A. Medical history
B. Mental state
C. Sensitivity to medications
D. Height and weight
B. Mental state
Drugs with a _____________ effect are those that must travel through the bloodstream to affect cells or tissues in various parts of the body.
A. Systemic
B. Delayed
C. Systematic
D. Local
A. Systemic
The ________________ effect is the desired effect of a drug, or the reason the drug is prescribed and administered.
A. Systemic
B. Side
C. Therapeutic
D. Adverse
C. Therapeutic
Drugs can have _____________ effects, which are additional effects on the body that are not part of the goal of drug therapy.
A. Systemic
B. Side
C. Therapeutic
D. Adverse
B. Side
What type of drug interaction occurs when two drugs administered together produce a more powerful response than
that of either given separately?
A. Synergism
B. Antagonism
C. Adverse
D. Potentiation
A. Synergism
_____________ occurs when administering two drugs at the same time results in one drug increasing the effect of the other.
A. Synergism
B. Antagonism
C. Adverse
D. Potentiation
D. Potentiation
A drug interaction in which two drugs inhibit or cancel each other’s effect is known as
A. Synergism
B. Antagonism
C. Adverse
D. Potentiation
B. Antagonism
_________________ drug dependence results when the body becomes so accustomed to a particular drug that it needs it to function.
A. Psychological
B. Physiological
C. Physical
D. Psychiatric
C. Physical
Commonly abused drugs include
A. Sedatives and hallucinogens
B. Alcohol and nicotine
C. Amphetamines and anabolic steroids
D. All of these
D. All of these
Healthcare workers can help prevent drug misuse and abuse by
A. Keeping medications locked away when they are not being used
B. Administering only prescribed medications
C. Observing patients for signs of drug dependence or misuse
D. All of these
D. All of these
Health professionals can help prevent patients from experiencing adverse reactions by
A. Being aware of possible reactions to each drug administered
B. Being sure to ask patients about any allergies or sensitivities
C. Notifying a supervisor if any sign of an adverse reaction is observed
D. All of these
D. All of these
After taking several doses of medicine, Bill no longer seems to be affected by the drug. This may be a symptom of what?
Tolerance
Mrs. Jones gets a stronger drug effect with each additional dose of her medication. She may be showing signs of what?
Cumulative effect
A drug interaction wherein two drugs inhibit or cancel the action of the other is called what?
Antagonism
You have recently given Mr. Smith a medication ordered by his doctor. Mr. Smith is not reacting to the drug
the way you expected. In talking with him, you discover that he has also been taking medication he brought
with him from home. You suspect that his adverse reaction is due to a(n) what?
Drug interaction
