Ch 19: IV Drug Compatibility, Stability, Administration, and Degradation

Question 1

common drugs with filter requirements

Answer 1

Pushy Guys in LA LA land. most: 0.22 micron filter during admin. Phenytoin, Golimumab (Symponi), Lipids, Amphotericin B (lipid forms), Lorazepam, Amiodarone. *larger pore size required. ampho prepare using 5 micron filter

Question 2

drugs that require non-pvc containers

Answer 2

LATIN: lorazepam, amiodarone, tacrolimus, insulin, nitroglycerin

Question 3

DEHP

Answer 3

di-ethylhexyl phthalate. plasticizer that makes the plastic tubes flexible. can leach into the IV soln or the soln adsorbs/adheres to the container - place these in polyolefin, polypropylene, or glass

Question 4

common drugs with diluent soln requirements (saline, not dextrose)

Answer 4

ACID APE. ampicillin, caspofungin (cancidas), infliximab (remicade), daptomicin (cubicin). amipicillin/sulbactam (unasyn), phenytoin, ertapenem.

Question 5

common drugs with diluent soln requirements (dextrose, no saline)

Answer 5

ABS. amphotericin B, bactrim, synercid (quinupristin/dalfopristin)

Question 6

compatibility

Answer 6

additive (drugs in same container) or syringe (drugs mixed in syringe) are different from Y site compatibility. check references: kings or trissels (handbook on injectable drugs)

Question 7

do not refrigerate drugs common

Answer 7

Dear Sweet Pharmacist, Marry Me - Forever Eternally. Dexmedetomidine (Precedex), sulfamethoxazole/trimethoprim (bactrim), phenytoin - crystallizes, metronidazole (flagyl), moxifloxacin (avelox), furosemide - crystallizes, enoxaparin (lovenox).

Question 8

protect from light during admin key drugs

Answer 8

Deliver Every Needed Med Protected. Doxycycline, Epoprostenol (Flolan), Nitroprusside (Nitropress), Micafungin (Mycamine), Phytonadione.