CH. 19 Flashcards
What is the product of the following reaction?
ketone –> alkene
What is the product of the following reaction?
catalytic hydrogenation
ketone or aldehyde –> alcohol
What is the product of the following reaction?
Oxidation
Primary alcohol –> carboxylic acid
What is the product of the following reaction?
Oxidation
Secondary alcohol –> ketone
What is the product of the following reaction?
Oxidation
secondary alcohol –> ketone
What is the product of the following reaction?
Oxidation
primary alcohol –> aldehyde
What is the product of the following reaction?
Clemmenson Reduction
ketone or aldehyde –> alkane
What is the product of the following reaction?
Raney-Nickel Reduction
ketone or aldehyde –> alkane
What is the product of the following reaction?
Catalytic Hydrogenation
alkene –> alkane
ALWAYS SYN ADDN
What is the product of the following reaction?
Catalytic Hydrogenation; poisoned catalyst
Alkyne –> cis-alkene
what is an oxidation reaction
losing electrons, carbon losing bonds to less electronegative atoms, and gaining bonds with more electroneg atoms
gaining O, O2
losing H2
what is a reduction reaction
Carbon gaining bonds to less electroneg atoms and losing bonds to more electroneg atoms
gaining H2
losing O, O2
What is the product of the following reaction?
Suzuki Coupling
What is the product of the following reaction?
Heck Coupling
What is the product of the following reaction?
Alkene Metathesis Cross
What is the product of the following reaction?
Alkene Metathesis Ring Closing
What is the name of this functional group?
an Imine
What is the name of this functional group?
Hydrazone
What is the name of this functional group?
Oxime
What reagents can you use for reductive amination?
NaBH4
or
NaBH3CN
What is the name of this aldol condensation product?
What is the name of the mechanism that is the only acception for OH as a leaving group?
E1cb
does low heat favor the beta-hydroxy aldehyde compound in aldol condensations or the alpha-beta-unsaturated aldehyde?
low heat favors the beta-hydroxy aldehyde compound
does heat favor the beta-hydroxy aldehyde compound in aldol condensations or the alpha-beta-unsaturated aldehyde?
heat favors the alpha-beta-unsaturated aldehyde
What is the name of this aldol condensation product?
How do you improve selectivity of crossed aldol reactions?
use a very strong base (ex: LDA)
or
no alpha H’s present
Is this aldol condensation kinetic or thermodynamic?
thermodynamic
the proton transfer is reversible
Is this aldol condensation kinetic or thermodynamic?
kinetic
proton transfer not reversible
where on this molecule does NaOH favor deprotonation?
where on this molecule does LDA favor deprotonation?
What type of rings is an intramoleular aldol reaction successful for?
Why are other rings not favorable?
5 or 6 membered rings are successful
other rings not successfull due to relative instability
for this starting material in a intramolecular aldol reactions, which site is preferred to act as the electrophile?
Which site is preferred to act as the enolate?
