CH 18 - CONTRAST AGENTS Flashcards
WHAT DOES CES STAND FOR?
CONTRAST ENHANCED SONOGRAPHY
WHAT DOES UCA STAND FOR?
ULTRASOUND CONTRAST AGENT
WHAT ARE THE BENEFITS TO USING UCA?
- DETECTING LOW VELOCITY BLOOD FLOW
- DETECTING FLOW IN VERY SMALL VESSELS
- IMPROVING SENSITIVITY
WHAT ARE THE CONTRAST AGENT REQUIREMENTS?
- NON TOXIC
- SMALL MICROBUBBLES SMALL ENOUGH TO GO THRU CAPILLARIES
- STABLE
HAS THE FDA APPROVED THE USE OF MICROBUBBLES?
YES, IN ECHOCARDIOGRAPHY
WHAT AGENTS HAVE BEEN APPROVED BY THE FDA?
OPTISON
DEFINITY
IMAGENT
- FOR USE IN ECHO
WHAT AGENTS ARE AVAILABLE IN EUROPE & ASIA?
LEVOVIST
SONOVUE
WHAT WAS THE 1ST GENERATION AGENT?
AGENTS THAT CONTAINED ROOM AIR
ALBUNEX - WAS REMOVED FROM THE MARKET
WHAT DOES 2ND GENERATION AGENTS CONSIST OF?
HEAVY GASSES
WHAT SPECIFIC CHARACTERISTICS INFLUENCE THE ACOUSTICS BEHAVIOR WITH GAS?
THE TYPE OF GAS & ITS SHELL COMPOSITION
WHAT ARE THE 5 REQUIREMENTS FOR MICROBUBBLES?
1) SAFE
2) METABOLICALLY INERT
3) LONG LASTING
4) STRONG REFLECTORS OF U/S
5) SMALL ENOUGH TO PASS THROUGH CAPILLARIES
THIS IS MICROBUBBLES THAT ARE ABSORBED FROM BLOOD TO SPECIFIC TISSUES IN THE BODY.
TISSUE SPECIFIC U/S CONTRAST AGENTS
THIS HAS PREDICTABLE BEHAVIOR - TARGET SPECIFIC TISSUES -
MOLECULAR IMAGING AGENTS - CATEGORY (TISSUE SPECIFIC AGENTS ARE IN THIS CATEGORY)
WHAT HAPPENS WHEN A MICROBUBBLE RUPTURES?
CAUSES A DOPPLER SHIFTS RESULTING IN RANDOM COLORS KNOWN AS ACOUSTIC EMMISION
THIS ONLY RECEIVES SECOND HARMONIC FRQ.
HARMONIC IMAGIN ( TWICE THE TRANSMITTED FRQ)