CH 18 - CONTRAST AGENTS Flashcards

0
Q

WHAT DOES CES STAND FOR?

A

CONTRAST ENHANCED SONOGRAPHY

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1
Q

WHAT DOES UCA STAND FOR?

A

ULTRASOUND CONTRAST AGENT

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2
Q

WHAT ARE THE BENEFITS TO USING UCA?

A
  • DETECTING LOW VELOCITY BLOOD FLOW
  • DETECTING FLOW IN VERY SMALL VESSELS
  • IMPROVING SENSITIVITY
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3
Q

WHAT ARE THE CONTRAST AGENT REQUIREMENTS?

A
  • NON TOXIC
  • SMALL MICROBUBBLES SMALL ENOUGH TO GO THRU CAPILLARIES
  • STABLE
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4
Q

HAS THE FDA APPROVED THE USE OF MICROBUBBLES?

A

YES, IN ECHOCARDIOGRAPHY

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5
Q

WHAT AGENTS HAVE BEEN APPROVED BY THE FDA?

A

OPTISON
DEFINITY
IMAGENT
- FOR USE IN ECHO

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6
Q

WHAT AGENTS ARE AVAILABLE IN EUROPE & ASIA?

A

LEVOVIST

SONOVUE

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7
Q

WHAT WAS THE 1ST GENERATION AGENT?

A

AGENTS THAT CONTAINED ROOM AIR

ALBUNEX - WAS REMOVED FROM THE MARKET

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8
Q

WHAT DOES 2ND GENERATION AGENTS CONSIST OF?

A

HEAVY GASSES

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9
Q

WHAT SPECIFIC CHARACTERISTICS INFLUENCE THE ACOUSTICS BEHAVIOR WITH GAS?

A

THE TYPE OF GAS & ITS SHELL COMPOSITION

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10
Q

WHAT ARE THE 5 REQUIREMENTS FOR MICROBUBBLES?

A

1) SAFE
2) METABOLICALLY INERT
3) LONG LASTING
4) STRONG REFLECTORS OF U/S
5) SMALL ENOUGH TO PASS THROUGH CAPILLARIES

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11
Q

THIS IS MICROBUBBLES THAT ARE ABSORBED FROM BLOOD TO SPECIFIC TISSUES IN THE BODY.

A

TISSUE SPECIFIC U/S CONTRAST AGENTS

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12
Q

THIS HAS PREDICTABLE BEHAVIOR - TARGET SPECIFIC TISSUES -

A

MOLECULAR IMAGING AGENTS - CATEGORY (TISSUE SPECIFIC AGENTS ARE IN THIS CATEGORY)

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13
Q

WHAT HAPPENS WHEN A MICROBUBBLE RUPTURES?

A

CAUSES A DOPPLER SHIFTS RESULTING IN RANDOM COLORS KNOWN AS ACOUSTIC EMMISION

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14
Q

THIS ONLY RECEIVES SECOND HARMONIC FRQ.

A

HARMONIC IMAGIN ( TWICE THE TRANSMITTED FRQ)

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15
Q

WHAT HAS A DETRIMENTAL EFFECT ON CONTRAST MICROBUBBLES & WHAT IS USED TO CORRECT THIS?

A

ACOUSTIC FIELD; HARMONIC IMAGING

16
Q

HARMONIC IMAGING HAS A HIGHER ____ TO _____ RATIO.

A

SIGNAL TO NOISE

17
Q

A TECHNIQUE THAT IS USED TO MINIMIZE THE DISRUPTION OF MICROBUBBLES BY USING A LOW OUTPUT POWER IS?

A

MECHANICAL INDEX

18
Q

HOW DOES THE MI CORRECT THE PROBLEM?

A
  • ONLY TRANSMITS & RECEIVES AT PREDETERMINED INTERVALS
  • REDUCES MICROBUBBLE EXPOSURE TO SOUND WAVES
  • ALLOWS ADDITIONAL BUBBLE TO ENTER THE FIELD
19
Q

WHAT IS TIPS?

A

TRANSJUGULAR INTRAHEPATIC PORTO-SYSTEMIC SHUNTS