ch 14 Flashcards
These drugs act directly at cholinergic receptors where they block the actions of acetylcholine
anticholinergic durgs
What are the 3 categories of anticholinergic drugs
muscarinic antagonists
ganglionic blocking agents
Neuromuscular blocking agents
How does Atropine work
By preventing receptor activation by endogenous acetylcholine
Where do muscarinic antagonists exert their influence
heart
exocrine glands
smooth muscles
eyes
True or Flase
Heart rate increases with muscarinic antagonist
True
Atropine blocks receptors in the cardiac resulting in decreased heart rate
True or False
Secretion from salivary glands will increase with atropine
false
True of false
Exocrine glands increase secretion with muscarinic agonist
True
This type of drug will result in relaxation of bronchi decrease tone of bladder and decrease motility of GI track
anticholinergic drug (muscarinic antagonists)
Effect of muscarinic antagonists on eyes
dilation of pupil (mydriasis)
relaxation of ciliary muscle focusing the lens for far vision
What drug class would help overactive bladder
anticholinergic drugs (muscarinic antagonist) because they block M3 receptor activation resulting in relaxation
First line treatment for overactive bladder
behavioral therapy- timed voiding, avoiding liquids
Which subtype of muscarinic receptor is responsible for bladder
M3