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Micro Bio CH 13 > ch 13 > Flashcards

ch 13 Flashcards

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Biology 101 flashcards
1
Q

Tobacco mosaic virus

A

-First virus to be studied by Wendell Stanley
-Only affects plants
-

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2
Q

Viron Structure

A

-Nucleic Acid (single or double-stranded, linear or circular, DNA or RNA)
-Capside (made of capsomeres)
-SOMETIMES an envelope (lipids, proteins, and carbs) maybe has spike proteins

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3
Q

Enveloped Viruses

A

-Herpes (HSV)
-Chicken Pox (VZV)
-Mononucleosis
-West Nile
-Hepatitis C
-Influenza
-Measles
-Mumps
-Rabies
-HIV

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4
Q

Noroviruses cause

A

gastroenteritis “stomach flu”

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5
Q

Icosahedrons

A

-West nile virus
-norovirus
-adenovirus
-polio
-HHV
-Zika

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6
Q

Examples of Complex

A

Bacteriophages (spaceships)
Poxvirus (no clearly defined capsid)

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7
Q

Poxvirus

A

Cause smallpox and cowpox

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8
Q

Chicken Pox

A

The Herpes virus is not apart of small smallpox family

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9
Q

Draw virus replication cycle on Ipad

A

DO IT

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10
Q

Steps of viral replication

A

Attachment (absorption)
Entry (penetration)
Uncoating
Biosynthesis (replication of viral genome and production of viral proteins, assembly of new virions)
Release

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11
Q

Corynebacterium diptheriae

A

Diptheria toxin

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12
Q

Streptococcus Pyogens

A

Scarlet fever (pyrogenic exotoxin)

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13
Q

How do animal viruses enter a host cell

A

endocytosis

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14
Q

How do animal viruses exit a host cell

A

exocytosis
lysis

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15
Q

Naked Viruses penetrate by

A

endocytosis

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16
Q

Enveloped viruses penetrate by

A

membrane fusion

17
Q

In Vitro vs in vivo

A

Vitro= “within glass”
vivo = “within the living”

18
Q

normal cells form

A

monolayer and stick to glass or plastic

19
Q

transformed cells (tumor cells)

A

pile on top of each other

20
Q

Primary cell line

A

only last 15-20 passages before they die out

21
Q

diploid cell line

A

50 passages

22
Q

continuous cell ine

A

can be cultured indefinitely (HeLa cells)

23
Q

cytopathic effect

A

causing cells to deteriorate as they multiply
(grainy, irregular clusters, cell enlargment)

24
Q

inclusion bodies

A

particles of aggregated proteins (dense and spherical)

25
Q

syncytia

A

multinucleate (lots of fusions of unicellular masses)

26
Q

Oncogenic Viruses

A

Hepatitis B
Epstein Barr
Human papilloma virus

27
Q

EBV

A

causes Burkitt’s lymphoma
aggressive
most common cause of childhood cancer in central Africa
effects jaw, CNS, bowel, kidneys, ovaries, etc.

28
Q

HPV

A

causes warts, usually benign but can become carcinomas

29
Q

Shingles

A

Caused by reactivation of chicken pox (Varicella zoster virus)
latent virus
unilateral rash

30
Q

Simplexvirus (HHV-1/-2)

A

latent virus
effects mouth and genital area

31
Q

Acyclovir

A

treats symptoms of chickenpox, shingles, and herpes virus

32
Q

Rubeola

A

Measles
high fever, cough, runny nose, and watery eyes appear 7-14 days after infection. Koplik spots and a rash will also appear

33
Q

Rubella

A

German Measles
a less intense version of Rubeola

34
Q

Viroids

A

circular RNA molecule with a. single and double-stranded regions
mostly plant pathogens
80x smaller than a virus
only human disease is hepatitis d

35
Q

Prp-C vs Prp-Sc

A

Prp-C: normal, sensitive to being broken down, mainly in neurons in the brain
Prp-SC: disease-causing form, develops spongiform disease (SC stands for Scrapie, infectious disease in sheep)

36
Q

Spongiform disease

A

Astrocytes digest dead neurons created by the Prp-SC leaving holes = spongiform disease (CJD most common spongiform disease in humans)

37
Q

Prp-Sc acquired by

A

eating infected tissue
inheriting mutation in the gene for Prp-C
transplants

Micro Bio CH 13 (4 decks)

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