CH 12b: muscles Flashcards

1
Q

What does phosophocreatine breakdown produce? what is the enzyme that breaks it down?

A

short burst of energy (creatine kinase - CK)

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2
Q

What are the most rapid, and efficient store of energy?

A

CHO (glucose)
- most rapid and efficient store of energy

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3
Q

What does anaerobic glycolysis produce? What are some characteristics of it?

A
  • produces lactate and acid
  • quick
  • no oxygen required
  • small amount of energy released
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4
Q

What is aerobic respiration — what does it produce?

A
  • citric acid cycle and electron transport chain
  • slow
  • oxygen required
  • large amount of energy needed
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5
Q

Can muscle store ATP?

A

YES! resting muscle stores energy from ATP in the high-energy bonds of phosphocreatine
- working muscle then uses the stored energy

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6
Q

What casuals central fatigue?

A

Due to CNS

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7
Q

What causes peripheral fatigue?

A
  • due to neuron or muscle
  • extended submax exercise leads to depletion of glycogen stores
  • Short-duration maximal exertion leads to increased levels of Pi
  • Maximal exercise leads to ion imbalances
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8
Q

How does muscle length influence contraction?

A
  • Decreased length of resting fiber: too much overlap does not give room for the myofibrals to shorted causing a contraction
  • Increased length of resting fiber: they are too far apart so the myosin heads can not grab onto the actin to perform a power stroke
  • Needs to have the optimal resting length (2.0-2.3 cm)
  • Figure 12.15
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9
Q

What is a single twitch?

A
  • in a skeletal muscle
  • muscle relaxes completely in between stimuli
  • single twitches with space in between
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10
Q

What is summation?

A

stimuli closer together do not allow muscle to relax fully (can be constant GPs or can be varied)

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11
Q

What is summation leading to unused tetanus?

A

Stimuli are far enough apart to allow muscle to relax slightly between stimuli

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12
Q

What is summation leading to complete tetanus?

A

Muscle reaches steady tension, if muscle fatigues, tension decreases rapidly
- also called fused tetanus
- no chance for a muscle to relax in between contractions

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13
Q

What is a motor unit?

A
  • consists of one motor neuron and all the muscle fibers it innervates
  • a muscle may have many motor units of different types
  • one muscle may have many motor units of different fiber types
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14
Q

How do motor units help decrease fatigue?

A

only a certain number are activated, and when those start to feel fatigued, then the CNS can subconsciously switch motor units on/off

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15
Q

How can smooth muscle me classified?

A
  • by location
  • by contraction pattern (tonic, phasic, etc)
  • by their communication with neighboring cells (single unit smooth muscle, unitary smooth muscle, visceral smooth muscle, or multi unit smooth muscle)
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16
Q

What kind of control are the esophageal and urinary bladder sphincters under?

A

tonic control

17
Q

Look at figure 12.22 so see what the different types of smooth muscle look like

A
18
Q

What are single-unit smooth muscle cells?

A
  • connected by gap junctions (enable AP to travel)
  • contracts at a single unit
  • don’t have to release neurotransmitter on every cell
19
Q

What is a multi-unit smooth muscle cell?

A
  • not electrically linked
  • each cell must be stimulated independently
  • EX: eye
20
Q

Does somatic or autonomic have varicosities or both?

A

ONLY autonomic!

21
Q

What are the caveolae?

A
  • areas just outside
  • membrane wraps around & hold it
    (i THINK, check in book!)
22
Q

What forms the cytoskeleton in smooth muscles?

A
  • intermediates
  • protein dense bodies
  • actin attaches to the dense bodies
  • each myosin molecule surrounded with actin filaments
23
Q

Go back and do slides 26-32

A
24
Q

What are slow wave potentials?

A
  • series of depolarizations and depolarizations
  • potentials fire APS when they reach threshold
25
Q

What are pacemaker potentials?

A
  • series of depolarizations and repolarizations
  • ALWAYS reach threshold
26
Q

What is pharmacomechanical coupling?

A

contraction caused by chemical signaling

27
Q

What is electromechanical coupling?

A

contraction caused by electrical signaling

28
Q

Is smooth muscle under antagonistic or agonistic control?

A
  • antagonistic control
  • by both sympathetic and parasympathetic
29
Q

How do most neurotransmitters and hormones act with smooth muscle ?

A
  • Act through GPCRs
30
Q

How are chemical signals influenced in smooth muscle activity?

A

tonic control by only a single autonomic branch

31
Q

table 12.3 and 12.4

A
32
Q

How is cardiac muscle similar to skeletal muscle?

A
  • striated
  • similar sarcomere structure
33
Q

How does cardiac muscle differ from skeletal muscle?

A
  • muscle fibers are shorter
  • may be branched
  • have single nucleus
34
Q

How is cardiac muscle like smooth muscle?

A
  • electrically linked to one another
  • some exhibit pacemaker potentials
  • under sympathetic and parasympathetic control as well as hormone control
35
Q
A