Ch. 11: Protein Sorting & Transport Online Quiz (MC)

Question 1

___ are synthesized in the Golgi Apparatus.

Answer 1

glycolipids

Question 2

The ribosomes of the rough endoplasmic reticulum are targeted to the cytoplasmic side of the membrane via a sequence within the ___ ___ ___.

Answer 2

protein being synthesized

Question 3

The lumen of the ER is equivalent topologically to the ___ ___.

Answer 3

extracellular space

Question 4

N-linked glycosylation at an Asn-X-Ser/Thr consensus sequence adds ___ sugar(s) in a single step to the protein.

Answer 4

14

Question 5

Proteins are translocated into the ER lumen through an aqueous channel created by the ___ protein.

Answer 5

Sec61

Question 6

Secretory granules are ___ a contiguous membrane domain.

Answer 6

NOT

Question 7

For many yeast proteins, post-translational translocation of proteins targeting the ER is a process affecting many ___ ___ ___.

Answer 7

newly synthesized proteins

Question 8

In some proteins the only transmembrane sequence is located C-terminally in the protein. These proteins are recognized by ___.

Answer 8

TRC40 (GET3)

Question 9

The major site at which membrane lipids are synthesized is the ___ side of the ER membrane.

Answer 9

cytosolic

Question 10

Signal patches, mannose phosphorylation, and the mannose-6-phosphate receptor, are all involved in targeting proteins to ___.

Answer 10

lysosomes