Ch. 11: Lipid and Amino Acid Metabolism Flashcards

1
Q

what is the primary form of dietary fat

A

triacylglycerols

also cholesterol, cholesterol esters, phospholipids, and fatty acids

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2
Q

what does hormone-sensitive lipase do

A

mobilizes lipids from adipocytes

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3
Q

what does lipoprotein lipase do

A

mobilize lipids from lipoproteins

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4
Q

what does VLDL do

A

transports newly synthesized trial glycerols molecules from the liber to peripheral tissues in the bloodstream

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5
Q

what does IDL do

A

picks up cholesterol esters from HDL

- VLDL remnant

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6
Q

what does LDL do

A

transports cholesterol for use by tissues

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7
Q

what does HDL do

A

revere transport of cholesterol

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8
Q

what do apoproteins do

A

control interactions between lipoproteins

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9
Q

what does HMG-CoA reductase do

A

primary enzyme in the biosynthesis of cholesterol

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10
Q

what does LCAT do

A

catalyzes the formation of cholesterol esters for transport with HDL

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11
Q

what does CETP do

A

catalyses the transition of IDL to LDL by transferring cholesterol esters from HDL

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12
Q

where are fatty acids synthesized

A

the cytoplasm

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13
Q

what are the five steps of fatty acid synthesis

A

activation, bond formation, reduction, dehydration, and second reduction

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14
Q

what is the only fatty acid humans can synthesize

A

palmitic acid

requires eight rounds of “synthesis” to form

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15
Q

where does fatty acid oxidation occur

A

in the mitochondria

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16
Q

when do ketone bodies fomr

A

during ketosis, a prolonged starvation due to excess acetyl-CoA

17
Q

what occurs during Ketolysis

A

new acetyl-CoA is regenerated for use as an energy source in peripheral tissues

18
Q

what organ uses an especially large amount ketone bodies for energy

A

the brain

19
Q

where does protein digestion occur

A

the small intestine

20
Q

what are cellular proteins catabolized

A

starvation conditions

21
Q

how are amino groups excreted

A

through the urea cycle