ch. 1 orientation to pharm Flashcards

1
Q

Pharmacology is part of multiple disciplines from

A

anatomy
physiology
psychology
chemistry
microbiology

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2
Q

Drug:

A

any chemical that can affect living processes

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3
Q

Pharmacology:

A

the study of drugs and their interactions with living systems (physical and chemical properties of drugs and their effects)
- drug absorption, distribution, metabolism, excretion

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4
Q

Clinical Pharmacology:

A

study of drugs in humans

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5
Q

Therapeutics: (pharmacotherapeutics)

A

the use of drugs to diagnose, prevent, or treat disease or to prevent pregnancy; medical use of drugs

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6
Q

3 main properties of an ideal drugs

A

effectiveness: most important!!**; drug does what it’s supposed to do

safety: does not produce harmful effects, even in very high doses (all rugs can cause injury)

selectivity: only does what it is supposed to do

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7
Q

reversible action:

A

want drug actions to subside within an appropriate time frame (anesthetics)

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8
Q

predictability:

A

want to know what it will do

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9
Q

ease of admin:

A

simple to take/give; helps with pt adherence and decrease admin errors

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10
Q

freedom from drug interact:

A

no interactions between drugs taken concurrently

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11
Q

low cost:

A

one of the most expensive drugs out there, mavenclad $60,000/mon

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12
Q

chemical stability:

A

lose efficacy (effictiveness) if sits on shelf too long; have expiration dates

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13
Q

simple generic name:

A

pt can’t communicate what they are taking (can’t pronounce)= increased risk of error

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14
Q

therapeutic objective of drug therapy is:

A

provide MAXIMUM benefit with MINIMAL harm

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15
Q

Administration:

A

too much= toxicity
too little= treatment failure

route
time

med errors: who/how

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16
Q

Pharmacokinetics:

A

impact of the body on the drugs
how much of administered dose gets to sites of action in body

17
Q

4 pharmacokinetic processes:

A
  1. drug absorption
  2. drug distribution
  3. drug metabolism
  4. drug excretion
18
Q

pharmacodynamics:

A

impact of the drugs on the body

placebo effect: pt given what they believe to be med, has psychological/physiological response they believe would happen with that med (pos or neg reaction)

19
Q

Individual properties can affect drug responses: (4)

A
  • physiological: age, gender, weight
  • pathological: liver/kidney function; etc.
  • genetic: no 2 patients are alike
  • drug interactions: some drugs can increase/decrease effectiveness or side effects