CH 1 Arthritic/skeletal/soft tissue conditions Flashcards

1
Q

DJD/OA is characterized by

A

degeneration of articular cartilage, with hypertrophy of subchondral bone and joint capsule of weight bearing joints

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Medications for OA:

A

cortiscosteroids, NSAIDS; Glucocorticoids are injected in to joints that are inflamed and not responsive to NSAIDS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Diagnostic tests reveal what for DJD/OA

A

diminished point space, decreased height of articular cartilage and osteophytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is ankylosing Spondylitis

A

progressive inflammatory disorder of unknown etiology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Ankylosing Spondylitis begins in the

A

axial skeleton

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The initial onset of ankylosing spondylitis is typically in what decade of life

A

before the fourth decade

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

First symptoms of ankylosing spondylitis

A

mid and low back pain, morning stiffness and sacroiliitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Advanced ankylosing spondylitis is characterized by

A

degeneration of peripheral and costovertebral joints

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

ankylosing spondylitis effects ___ 3x more than __

A

men, women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

2 drugs besides NSAIDS/corticosteroids for ankylosing spondylitis

A

Cytotoxic drugs - block cell growth and Tumor necrosis factor inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Diagnostic test for ankylosing spondylitis:

A

HLA-B27

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is Gout

A

genetic disorder of purine metabolism characterized by elevated serum uric acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Where is gout most frequently observed

A

knee and great toe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Specific NSAID for gout

A

indomethacin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Diagnostic test for gout

A

lab tests identify monosodium rate crystals in synovial fluid or connective tissue samples

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is psoriatic arthritis

A

chronic, erosive inflammatory disorder of unknown etiology

17
Q

2 drugs for psoriatic arthritis

A

DMARDS - disease modifying anti rheumatic drugs; BRM: biological response modifiers

18
Q

What is rheumatoid arthritis

A

chronic systemic disorder involving a symmetrical pattern of dysfunction of synovial tissues of hands, wrists, elbows, shoulder, knees ankles and feet

19
Q

Most effected joints in RA

A

MCP and PIP

20
Q

Characteristic of RA

A

pannus formation, ulnar drift and volar subluxation of MCP joints; DIPs usually spared; swan neck and boutonniere deformity , Bouchard’s nodes (excessive bone formation on dorsal aspect of PIP)

21
Q

Juvenile RA onset is prior to age

A

16

22
Q

RA meds:

A

DMARDs, gold compounds, NSAIDS, immunosupresants, corticosteroids

23
Q

RA lab test results

A

increased WBCs and erythrocyte sedimentation rate. Hemoglobin/hematocrit shows anemia and RA factor is elevated

24
Q

what is osteoporosis

A

a metabolic disease that depletes bone mineral density/mass

25
Q

what is senile osteoporosis caused by

A

decrease in bone cell activity secondary to genetics or acquired abnormalities

26
Q

DDx ankylosing spondylitis and Spinal stenosis in history intake

A

Ankylosing spondylitis: morning stiffness, sharp pain to an ache, bilateral SI pain referring to posterior thigh. Spinal Stenosis: intermittent aching pain, may have neurogenic intermittent claudication

27
Q

imaging DDx ankylosing spondylitis and stenosis

A

AS: plain films, stenosis: CT scan

28
Q

Osteomalacia is characterized by

A

decalcification of bones due to Vit D deficiency

29
Q

Osteomyelitis

A

an inflammatory response within bone caused by an infection

30
Q

most common infection cause in osteomyelitis

A

staphylococcus aureus

31
Q

Arthrogryposis multiplex congenita

A

contractures, sausage like limbs

32
Q

Osteogenesis imperfectA

A

Autosomal dominant; abnormal collagen synthesis leading to an imbalance between bone deposition and reabsorption.

33
Q

osteochondritis dissecans

A

separation of articular cartilage from underlying bone; typically medial femoral condyle

34
Q

when is surgical care of myositis ossificans warranted

A

only non hereditary and after maturation of the lesion (6-24 months)

35
Q

difference between CRPS I and II

A

both have dysfunction in the sympathetic nervous system but I has no underlying nerve injury and II has a nerve injury

36
Q

Paget’s disease

A

abnormal osteoclastic and osteoblastic activity

37
Q

For less than ___degrees scoliotic curve, PT is indicated

A

25

38
Q

spinal orthosis for scoliosis is indicated for _______degrees

A

25-45 degrees