Cervical, Vulval and Vaginal Pathology Flashcards
What are the 5 types of pathology in the cervix?
Developmental abnormalities Inflammation/infection Benign polyps Pre-malignant conditions Malignancy
What are the 2 types of developmental abnormalities of the cervix?
Give 2 examples of each.
PARTIAL reproductive tract abnormalities, e.g.
- Unicornuate uterus
- Cervical atresia
COMPLETE DOUBLE reproductive tract abnormalities, e.g.
- Bicornuate uterus
- Double uterus
List 8 examples of infection in the cervix.
Human papilloma virus Chlamydia Gonorrhoea Herpes simplex type 2 Trichomonas vaginalis Candida albicans Actinomyces Bacterial vaginosis
What are the 5 types of pathology in the vulva?
Inflammation Infection Cysts Pre-malignant conditions Malignancy
What causes inflammation of the vulva?
Give 3 examples.
Inflammatory skin conditions, e.g.
- Psoriasis
- Eczema
- Contact dermatitis
Give 4 examples of vulval infection.
HPV 11 (vulval warts)
Candida
Hair follicle infection
Bartholin’s abscess
List 2 types of vulval cysts.
Epidermal inclusion cyst
Bartholin’s cyst
What type of epithelium lines a Bartholin’s cyst? (2)
Transitional or squamous
What type of pre-malignant lesion affects the vulva?
How is it graded?
Vulval intraepithelial neoplasia (VIN)
VIN1 - low grade
VIN2 - high grade
VIN3 - high grade
What types of malignancy can affect the vulva? (2)
Invasive squamous cell carcinoma
Squamous cell carcinoma associated with dermatoses
Describe the clinical features of invasive squamous cell carcinoma of the vulva. (2)
What conditions is invasive SCC associated with? (4)
CLINICAL FEATURES:
Warty tumours
Basaloid tumours
ASSOCIATED CONDITIONS: CIN Invasive cervical cancer VIN High risk HPV (types 16, 18)
Describe the clinical features of squamous cell carcinoma associated with dermatoses. (2)
What conditions are associated with SCC with dermatoses? (3)
CLINICAL FEATURES:
Well-differentiated
Keratinising tumour
ASSOCIATED CONDITIONS:
Dermatoses
Adjacent squamous hyperplasia
Lichen sclerosus
What is lichen sclerosus?
A condition causing thin, patchy white skin; may be extremely itchy
What are the 2 types of pathology affecting the vagina?
Pre-malignant conditions
Malignancy
What do you call pre-malignant change in the vagina?
How is it graded?
Vaginal intraepithelial neoplasia (VAIN)
VAIN1 - low grade
VAIN2 - high grade
VAIN3 - high grade