Cervical, Vulval and Vaginal Pathology Flashcards

1
Q

What are the 5 types of pathology in the cervix?

A
Developmental abnormalities
Inflammation/infection
Benign polyps
Pre-malignant conditions
Malignancy
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2
Q

What are the 2 types of developmental abnormalities of the cervix?

Give 2 examples of each.

A

PARTIAL reproductive tract abnormalities, e.g.

  • Unicornuate uterus
  • Cervical atresia

COMPLETE DOUBLE reproductive tract abnormalities, e.g.

  • Bicornuate uterus
  • Double uterus
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3
Q

List 8 examples of infection in the cervix.

A
Human papilloma virus
Chlamydia
Gonorrhoea
Herpes simplex type 2
Trichomonas vaginalis
Candida albicans
Actinomyces
Bacterial vaginosis
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4
Q

What are the 5 types of pathology in the vulva?

A
Inflammation
Infection
Cysts
Pre-malignant conditions
Malignancy
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5
Q

What causes inflammation of the vulva?

Give 3 examples.

A

Inflammatory skin conditions, e.g.

  • Psoriasis
  • Eczema
  • Contact dermatitis
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6
Q

Give 4 examples of vulval infection.

A

HPV 11 (vulval warts)
Candida
Hair follicle infection
Bartholin’s abscess

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7
Q

List 2 types of vulval cysts.

A

Epidermal inclusion cyst

Bartholin’s cyst

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8
Q

What type of epithelium lines a Bartholin’s cyst? (2)

A

Transitional or squamous

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9
Q

What type of pre-malignant lesion affects the vulva?

How is it graded?

A

Vulval intraepithelial neoplasia (VIN)

VIN1 - low grade
VIN2 - high grade
VIN3 - high grade

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10
Q

What types of malignancy can affect the vulva? (2)

A

Invasive squamous cell carcinoma

Squamous cell carcinoma associated with dermatoses

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11
Q

Describe the clinical features of invasive squamous cell carcinoma of the vulva. (2)

What conditions is invasive SCC associated with? (4)

A

CLINICAL FEATURES:
Warty tumours
Basaloid tumours

ASSOCIATED CONDITIONS:
CIN
Invasive cervical cancer
VIN
High risk HPV (types 16, 18)
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12
Q

Describe the clinical features of squamous cell carcinoma associated with dermatoses. (2)

What conditions are associated with SCC with dermatoses? (3)

A

CLINICAL FEATURES:
Well-differentiated
Keratinising tumour

ASSOCIATED CONDITIONS:
Dermatoses
Adjacent squamous hyperplasia
Lichen sclerosus

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13
Q

What is lichen sclerosus?

A

A condition causing thin, patchy white skin; may be extremely itchy

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14
Q

What are the 2 types of pathology affecting the vagina?

A

Pre-malignant conditions

Malignancy

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15
Q

What do you call pre-malignant change in the vagina?

How is it graded?

A

Vaginal intraepithelial neoplasia (VAIN)

VAIN1 - low grade
VAIN2 - high grade
VAIN3 - high grade

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16
Q

What type malignant cancer is commonly found in the vagina?

A

Squamous cell carcinoma