Cervical Cancer Flashcards

1
Q

HPV infx causes metaplastic changes to the cells in the ________

A

cervical transformation zone (junction b/w squamous epithelium of ectocervix and glandular epithelium of endocervix)

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2
Q

order a ___ for cervical CA

A

Colposcopy + Bx

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3
Q

PAP screening guidelines

< 21 yo

A

do NOT screen

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4
Q

PAP screening guidelines

21-29 yo

A

PAP alone q 3yrs

dont do HPV screen bc its very common in this age grp and will likely clear on its own

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5
Q

PAP screening guidelines

30-65

A

3 options
1. PAP alone q 3 yrs
2. HPV test alone q 5yrs
3. CO-Test (PAP + HPV) q 5yrs

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6
Q

PAP screening guidelines

> 65yo

A

None if average risk pt and norm screens for past 10yrs and no risk factors

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7
Q

PAP screening guidelines

Post-hysterectomy

A

Hysterctomy d/t CIN or CA -> vaginal cuff PAP
No CIN/CA + TOTAL hysterectomy -> NONE
No CIN/CA + subtotal hysterectomy (cervix intact) -> norm screen based on age

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8
Q

You can stop PAP screens if youve had healthy screens your entire life and are now ___yo

A

65

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9
Q

List the PAP terminology reports from least to most severe

A
  1. Negative for intraepithelial lesion or malig
  2. ASC-US
  3. LSIL
  4. ASC-H
  5. HSIL
  6. SCC
  7. AGC
  8. Adenocarcinoma in Situ or Adenocarcinoma
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10
Q

PAP reports

LSIL is associated with CIN _____
HSIL is associated with CIN ___

A

LSIL -> CIN I
HSIL -> CIN II/III

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11
Q

is LSIL and HSIL squamous or glandular?

A

squamous

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12
Q

ASC-US Trmnt

A

21-24yo -> repeat PAP in 1yr
25+ -> HPV (+) -> Colposcopy + Bx. HPV (-) -> CO-TEST q 3yrs

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13
Q

Only do a colposcopy + Bx on a pregnant pt if their PAP report shows ____

A

HIGH GRADE LESIONS
HSIL, AGC, OR HIGHER

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14
Q

Pregnant pt had a PAP and report says CNII/III. Trmnt?

A

defer trmnt until postpartum

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15
Q

Preferred trmnt of cervical cancer if pt was to become pregnant in the future

A

Ablation > excision

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16
Q

Vaccine to prevent cervical cancer

A

Gardasil 9 (HPV)