Cerebrovascular disease: continuum deck 3 (cardioembolic, LAOD Flashcards
% of strokes that are cardioembolic
20-30%
Sources of embolic
any where proximal to the ischemic territory ( atria, ventricles, valves, aorta, extracranial cervical arteries
Embolic strokes are more likely to cause what two things ?
seizures and hemorrhagic transformations
Lab work up for cardioembolic stroke
CBC, BC, ESR, CRP, PT/INR, TSH, Lipids, Hypercoag (APC resistant)
risk of stroke in a-fib w/o AC
5%
Important scores in CE stroke
hasbled, chadsvasc
Four main ACs
warfarin, dabigatrin (pradaxa), apixaban (eliquis), rivaroxaban (xarelto)
AC with shortest half-life and once daily dosing
Xarelto (rivaroxaban) (5-9 hours)
Renal dosing for ACs
Crcl <30 Dabigatran 75mg/d
Crcl <50 Xarelto 15mg/d
Creatine >1.5, age >80, <132 lbs Eliquis 2.5mg
how many times would someone have to fall for the risk to outweigh the benefit for AC and subdural hematomas
295 times
When to resume AC after stroke
14 days but bigger strokes may need 4 weeds but asa should be administered in the meantime
atheroma definitions
> 4mm, noncalcified, mobile components