Cerebral Palsy Flashcards
What is the International Workshop of Definition and Classification’s definition of cerebral palsy?
A group of permanent disorders of the development of movement and posture, causing activity limitations that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain
What are some comorbidities that are associated with CP?
- sensation/sensory processing involvement
- perception
- cognition
- communication/speech issues
- behavior/emotional disorders
- mental retardation
What is the incidence for CP in single births in 1,000? Twins? Triplets? Quadruplets?
single = 2-3 twins = 15 triplets = 80 quadruplets = 43
What is the main etiology of CP? What percent is related to the main cause?
changes in prenatal brain development, accounts for 75%
What are the other etiologies of CP?
- congenital brain anomalies
- prenatal events
- perinatal events
- post/neonatal events (10-18%)
When is the definitive diagnosis for CP made?
After 12 months of age (some doctors wait until after age 2, delayed diagnosis due to neuroplasticity)
What studies are available for the diagnosis of CP?
MRI, Cranial Ultrasound
What is the presentation for CP in infants?
- abnormal muscle tone
- atypical posture
- movement with persistent reflexes
- non-progressive
What other diagnoses can mimc CP?
- metabolic disorders
- mitochondrial disorders
Intraventricular Hemorrhage
bleeding into the ventricles
Germinal Matrix Hemorrhage
bleeding into the tissue around the ventricles
Periventricular Intraventricular Hemorrhage
bleeding into both areas (tissue around ventricles and ventricles)
Periventricular Cyst
may form in the area where the bleed occurred once the acuteness has resolved
What are the grades for hemorrhages? Which is most severe?
I through IV, IV most severe
Is neuroimaging singly predictive for the development of CP?
No
What are the risk factors for CP?
- mechanical ventilation
- injury during critical periods of brain development
What area of the brain is most sensitive to insult and at what time is it most sensitive?
- periventricular white matter
- 24-34 weeks gestation
What are the antenatal risk factors for CP?
- prematurity and low birth weight
- intrauterine infections
- multiple gestation
- pregnancy complications
What are the perinatal risk factors for CP?
- birth asphyxia
- complicated labor and delivery
What are the postnatal risk factors for CP?
- non-accidental injury
- head trauma
- meningitis/enchaphalitis
- cardiopulmonary arrest