Cerebellum Flashcards
What are the three functional divisions of the cerebellum
Vestibulocerebellum, Spinocerebellum, Cerebrocerebellum
How does the cerebellum create normal patterned movement to occur
release of inhibition allows for normal patterned movement
What synapses onto the deep cerebellar nuclei and provide an inhibitory influence
Purkinje Cells
Output of the cerebellum goes where?
neurons in the deep cerebellar nuclei
What are the three nuclei of the deep cerebellar nuclei
- fastigial nucleus
- interposed nucleus
- dentate nucleus
The deep cerebellar nuclei ultimately influence LMN activity through indirect connections to what 4 descending motor systems?
- vestibulospinal tracts
- reticulospinal tracts
- rubrospinal tracts
- corticospinal tracts
What is the primary efferent pathway of the cerebellum that runs through the superior cerebellar peduncle?
dentatorubrothalamic pathway
The dentate is involved with what?
motor planning
What makes up the vestibulocerebellum
Flocculonodular lobe
What is the input to the vestibulocerebellum
Vestibular nuclei and apparatus
What is the output from the vestibulocerebellum
Back to the vestibular nuclei
What is the function of the vestibulocerebellum
Balance and equilibrium. Eye movements
Lesion to the vestibulocerebellum results in what 3 possible outcomes
Nystagmus, disequilibrium, poor trunk balance
The spinocerebellum is made up of what?
Vermis and paravermal zones plus much of the anterior lobe
What is the input to the spinocerebellum
Spinal cord, auditory, visual, vestibular, trigeminal, and motor cortex Axial/postural muscle info from the medial lemniscus
Where is the output from the spinocerebellum go to?
Medial and lateral descending pathways (reticulospinal, vestibulospinal) through both the interposed and fastigial nuclei
What is the function of the spinocerebellum?
Influences the controlling of limb movements and muscle tone for error correction resulting in coordinated movements. Functions more at proximal limb joints
Lesion to the spinocerebellum results in what
Ataxia gait pattern
What is the cerebrocerebellum made up of?
Lateral parts of the cerebellar hemispheres (primarily the posterior lobe)
What is the input to the cerebrocerebellum?
Widespread areas of the cortex via the pontine nuclei
What is the output of the cerebrocerebellum?
Motor and premotor cortex through the dentatorubrothalamic pathways
What is the function of the cerebrocerebellum?
Planning and coordination of voluntary movements as well as the memory of movements
What is the result of a lesion to the vermal and flocculonodular lobe
Trunk ataxia
What is the result of a paravermal lesion
Gait and limb ataxia
What is the result of lateral cerebellar lesion?
Hand ataxia
This layer of the cerebellar cortex receives the majority of input from afferent systems (mossy fibers) and is made up of many granular cells.
Granular Cell Layer
What are the two pathways that run through the superior cerebellar peduncle?
- Dentatorubrothalamic Pathway (primary efferent pathway)
2. Ventral and Rostral spinocerebellum pathway- integrated sensory and motor from ipsilateral cord
What pathway of the inferior cerebellar peduncle carries specific joint and muscle info encoded by GTOs, muscle spindles and joint capsule receptors?
Dorsal and Cuneocerebellar Pathways
Dorsal- LE
Cuneiform-UE