Cerebellum Flashcards
What cells does the cerebellum contain?
Purkinje cells
Granule cells
What is the structure of a purkinje cells
Huge, highly branched but flat dendritic arbor(axel).
In the cerebellum the Purkinje cell are lined up like pages in a book, with their arbors lying in __ plane
parallel
What two input do purkinje cells recieve
Weak inputs from parallel fibres
Strong input from a climbing fibre, a single axon which winds around the purkinje cell and makes multiple contacts with it.
In response to multiple weak inputs from a parallel fibres what happens?
It fires a normal spike, or a simple spike
A single spike from the climbing fiber is called what?
A complex spike
What is the cerebellum import for?
Fine motor control and proprioception
There is a specific gait associated with cerebellar damage.
It is believed that the connections from parallel fibers to Purkinke cells act as a perceptron. Thus if y is the output of the Purkinke cell and in this simple model taking in to account that Purkinje cells are inhibitory the equation is..
y= -sum(w_ix_i)
where xis are the activities in the parallel fibres and wi is the the strength of the synapse from the ith climbing fiber to the Purkinje cell.
According to the perceptron rule there is a desired output d and the synapses are adjusted according to
dleta wi=-eta(d-y)xi
..
What can synapses from parallel fibers only be?
Positive, this can be accounted for by including inhibitory cells in the network.