Cerebellum Flashcards

1
Q

What is the function of the cerebellum?

A
balance and posture
coordinated voluntary movements
motor learning (fine tuning)
motor tonus
cognitive function: language
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2
Q

How are the peduncles of the cerebellum arranged?

A

sup. peduncle: to midbrain
middle peduncle: to pons, largest peduncle
inferior peduncle: medulla

input to cerebellum via mid. and inf. peduncles
output of cerebellum via sup peduncle

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3
Q

Which are the nuclei of the cerebellum?

A

dentate nc
interposed nc (emboliform and globose)
fastigeal nc

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4
Q

What cells can be found at the cerebellar cortex?

A

3 layers:
granule cell layer: granule and golgi cells
purkinje cell layer: purkinje cells (only ones leaving cerebellar cortex)
molecular cell layer: stellate and basket cells

except of granule cells, all others use GABA

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5
Q

What type of fibers give input to cerebellum?

A

climbing fibers
mossy fibers
aminergic fibers

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6
Q

What happens when there is a lesion in the archicerebellum?

A

problems with:
truncal ataxia towards the site of lesion
stance and gait
posture
head postures
oculomotor dysfunction (nystagmus and ocular dysmetria)

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7
Q

What happens when there is a lesion in the paleocerebellum?

A
problems with:
truncal ataxia
executing movements
regulation of posture and muscle tone
hypotonia
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8
Q

What happens when there is a lesion in the neocerebellum?

A
problems with:
limb ataxia
dysarthria
hypotonia
intention tremor
oculomotor disorder
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9
Q

Describe dyssynergia

A

lack of speed and skill while performing activities requiring coordinated activity
no synergistics on smooth movements, instead: jerky erratic, disorganized

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10
Q

Describe dysmetria

A

error judging the distance, speed, power, direction of movement
movements are too slow or too quickly with too much or too little force

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11
Q

Describe dysdiadochkinesia

A

inability to make fast repetitive movements

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12
Q

Describe intention tremor

A

most commom type of cerebellar tremor, occurs when making purposeful movement

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13
Q

Describe dysarthria

A

slow articulation, ataxic, slurred explosive speech due to dyssynergy of muscles of phonation

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14
Q

Describe hypotonia

A

muscle flaccidity, decreased tonic output, flabby muscles, unnatural attitudes

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15
Q

What is the difference between cerebellar and sensory ataxia

A

very similar

sensory ataxia: due to problem of peripheral nerves
eyes open shows no problem in movement and coordination, eyes closed reveals problem

cerebellar ataxia: eyes open or closed makes no difference

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16
Q

Causes for cerebellar syndrome

A

stroke, trauma, inflammatory diseases (encephalitis, HIV) neoplasm, paraneoplastic cerebellar degeneration, poisoning, degenerative diseases