cephalosporins

Question 1

organisms not covered by cephalosporins

Answer 1

LAME
listeria
atypicals (chlamydia, mycoplasma)
MRSA 
enterococci

Question 2

what is the one cephalosporin that’s exception to LAME

Answer 2

MRSA covered by ceftaroline (5th gen)

Question 3

1st gen ceph (2)

Answer 3

cefazolin - used prior to surgery to prevent S aureus wound infections

cephalexin

Question 4

what do cefazolin and cephalexin (1st gen ceph) cover?

Answer 4

GPC + PEcK
Proteus mirabilis
Ecoli
Klebsiella pneumoniae

Question 5

2nd gen ceph (3)

Answer 5

cefoxitin
cefaclor
cefuroxime

Question 6

what do cefoxitin, cefaclor, and cefuroxime (2nd gen ceph) cover?

Answer 6

GPC + HEN PEcKS
haemophilus influenzae
enterobacter aerogenes
neisseria spp
proteus mirabilis
ecoli
klebsiella pna
serratia marcescens

Question 7

3rd gen ceph

Answer 7

ceftriaxone
cefotaxime
ceftazidime

Question 8

what do the 3rd gen ceph cover?

Answer 8

use for serious gram negative infections resistent to toehr b-lactams

Question 9

ceftriaxone bugs

Answer 9

meningitis, gonhorrhea

Question 10

ceftazidime bugs

Answer 10

pseudomonas

Question 11

4th gen ceph

Answer 11

cefepime

Question 12

cefepime cover?

Answer 12

gram positives

pseudomonas

Question 13

5th gen ceph

Answer 13

ceftarolin

Question 14

ceftarolin cover?

Answer 14

BS: Gram pos, gram neg, MRSA

DOES NOT COVER PSEUDOMONAS

Question 15

cephalosporin toxicity

Answer 15

HSR, vit K deficiency (side chain of cephalosporins block vit K epoxide reductase)
-increases nephrotoxicity of aminoglycosides