Cephalosporins Flashcards
First gen
Cefadroxil
treats pharyngitis, tonsilitis, UTI and skin infections
side effects: rash pruritus, nausea, vomiting, diarrhea, C. Diff, superinfection
well absorbed in the GI tract and not affected by food
First Gen
Cefazolin sodium
treats endocarditis, septicemia, and skin, bone/joint, biliary, respiratory, and UTIs
side effects: rash, pruritus, C. Diff, superinfection, nausea, vomiting, diarrhea, injection site reaction
First Gen
Cephalexin
treats otitis media and skin, bone/joint, respiratory, and UTIs
side effects: C. Diff, rash, urticaria, nausea, vomiting, diarrhea, and superinfection
Second Gen
Cefaclor
treats pharyngitis, tonsillitis, otitis media, and skin, skin structures, respiratory and UTIs
side effects: headache, pharyngitis, rhinitis, rash, nausea, diarrhea, C. Diff, pruritus, and superinfection
Second Gen
Cefotetan
treats gynecologic, intraabdominal, respiratory, UTIs, skin
side effects: C. Diff, nausea, diarrhea, phlebitis, rash, pruritus, injection site reaction, and superinfection
Second Gen
Cefoxitin sodium
treats intraabdominal, gynecologic, skin, respiratory, bone/joint, and UTIs
side effects: rash pruritus, nausea, diarrhea, C. Diff, and superinfection
Second Gen
Cefprozil monohydrate
treats otitis media and respiratory and skin infections
side effects: rash pruritus, nausea, diarrhea, C. Diff, and superinfection
Second gen
Cefuroxime
treats meningitis, Lyme disease, otitis media, gonorrhea, septicemia, and skin, respiratory, pharyngitis, tonsillitis, sinusitis, UTI, and bone/joint infections
side effects: rash, C. Diff, phlebitis, vaginitis, nausea, vomiting, diarrhea, injection site reaction, and superinfection
Third Gen
Cefdinir
treats otitis media, acute sinusitis, tonsillitis, and respiratory, and skin infections
side effects: headache, rash, nausea, diarrhea, C. Diff, superinfection
Third gen
Cefixime
treats otitis media, tonsillitis, gonorrhea, and respiratory and UTIs
side effects: headache, dizziness, vomiting, diarrhea, flatulence, rash urticaria, arthralgia, vaginitis, C. Diff., and superinfection
Thrid Gen
Cefotaxime
bacteremia, septicemia, meningitis, typhoid fever, and gynecologic, skin, bone/joint, intraabdominal, respiratory, and UTIs.
side effects: rash, pruritus, fever, nausea, vomiting, diarrhea, colitis, C. Diff, injection site reaction, and superinfection
Third gen
Cefpodoxime
otitis media, tonsillitis, sinusitis, gonorrhea, proctitis, and skin, respiratory, and UTIs
side effects: headache, rash, nausea, vomiting, diarrhea, C. Diff, and superinfection
Food enhances drug absorption
Third gen
Ceftazidime
bacteremia, meningitis, gynecologic, intraabdominal, skin, respiratory, bone/joint, and UTIs
side effects: injection site reaction, diarrhea, fever, rash, pruritus, phlebitis, C. Diff, and superinfection
Third gen
Ceftriaxone
otitis media, meningitis, appendicitis, gonorrhea, septicemia, and surgical infection prophylaxis, and skin, respiratory, bone/joint, gynecologic, intraabdominal, and UTIs
effective against Klebsiella, Haemophilus, Clostridium, Citrobacter, Bacteroides, Acinetobacter, Neisseria, Proteus, Salmonella, Serratia, Shigella, Staphylococci, and E. Coli
Action: inhibit bacterial cell wall synthesis causing cell lysis; bactericidal effect
side effects: nausea, dyspepsia, dysgeusia, stomatitis, glossitis, vomiting, diarrhea, abdominal cramps, flatulence, rash, flushing, diaphoresis, fever, pruritus, headaches, dizziness, edema, injection site reaction, epistaxis, chills, vaginitis
CAUSE RENAL IMPAIRMENT
Third gen
Ceftibuten
otitis media, tonsillitis, and respiratory infections
side effects: headache, C. Diff, dyspepsia, superinfection, abdominal pain, nausea, vomiting, diarrhea