Cephalosporin Flashcards
What is the drug (2) in the first generation cephalosporin?
Cephalexin
Cefazolin
G+
MOA?
Inhibit cell wall synthesis
What is the drug in the second generation cephalosporin?
Cefaclor
G+,g-
What is the drug in the third generation cephalosporin?
Cefriaxone
G-,some G+
What is the drug in the fourth generation cephalosporin?
Cefepime
Broad spectrum
What is the drug in the fifth generation cephalosporin?
Ceftaroline
Ceftaroline (Telfaro) is used for what type of infection?
MRSA
Cefepime is used for what type of infection?
UTI
Which generation drug has a long half life and is eliminated via the liver?
3rd, cefriaxion
Which drugs do cephalosporins interact with?
Anticoagulants
Alcohol
Which drug treats MRSA
Ceftaroline (Telfaro)
Which generation drugs pass though the blood brain barrier?
3 (cefriaxone)
4 (Cefepime)