Central & Peripheral Fatigue + Pacing Flashcards

1
Q

What can cause fatigue?

A
  • Failure to supply O2
  • Failure to regulate H+
  • Failure to regulate lactate
  • Glycogen depletion
  • Failure to dissipate heat
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2
Q

Define central fatigue and provide examples

A

Central

  • Failure on CNS to adequately drive the muscle
  • Disturbances to neurotransmitters
  • Decrease in brain temperature
  • Core and brain heat
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3
Q

What is afferent feedback?

A
  • Driving stimuli from muscle -> CNS. Away from muscle, a regulatory mechanism.
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4
Q

What is efferent feedback?

A

CNS->muscle

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5
Q

Define peripheral fatigue and provide examples

A
  • An impairment located in the muscle and defined by a metabolic end point
  • Substrate depletion
  • Muscle metabolites
  • Feedback from fatigue sensitive afferents
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6
Q

What happens when exercising with existing fatigue, without and with epidurals?

A
  • Reduced performance
  • Same fatigue end point
  • Increased central drive
  • Over exertion
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7
Q

What happened with fentanyl + 5k? Is there a critical limit?

A
  • CNS tolerated extreme fatigue
  • Different pacing strategy
  • There is a critical limit
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8
Q

What is a pacing strategy and what dictates it?

A
  • Distribution of work rate
  • Starts with feed forward
  • Afferent feedback from central and peripheral sensors
  • Environmental stimuli
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