Central Nervous System drugs Flashcards
These drugs are used for psychiatric disorders, suppression of seizures, relief of pain, production of anesthesia
Cranial NS Drugs
Give three monoamine neurotransmitters:
Dopamine
Epinephrine
Serotonin
Give some nonopioid peptides:
Oxytocin
Somatostatin
Substance P
Vasopressin
It impedes/prevents the entry of drugs into the brain
Blood brain barrier
What are some adaptations used to prolong drug use?
-Increased therapeutic effects
-Decreased side effects
-Tolerance and physical dependence
It is the dysregulation of the transmitters serotonin, norepinephrine, and dopamine
ADHD (Attention Deficity/Hyperactivity disorder)
It is characterized by a dysregulation of transmitters by falling asleep during normal waking activities
Narcolepsy
Give at least two drugs used to treat narcolepsy:
Methylprenidate
Modafinil
This disease causes a neurodegenerative disorder characterized by tremor, rigidity, postural instability, and slowed movement
Parkinson’s disease
The drugs deployed for Parkinson’s disease
Dopaminergic drugs
Anticholinergic agents
It is a group of disorders characterized by excessive excitability of neurons in the CNS
Epilepsy
It is the excitation that undergoes limited spread from the focus to adjacent cortical areas
Partial seizures
It is the excitation that spreads widely throughout both hemispheres of the brain
Generalized seizures
These includes the suppression of sodium and calcium influx, the antagonism of Glutamate, and potentiation of GABA
Anti-epileptic drugs mechanism
What are the carboxylic acid derivatives under treatment of seizures?
Valproate
Valproic Acid
Divalproex
