Autonomic Nervous System drugs Flashcards

1
Q

What are the two divisions of the peripheral nervous system?

A

Afferent/Sensory
Efferent/Motor

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2
Q

What are the two components of the efferent division of the PNS

A

Autonomic Nervous System
Somatic Nervous System

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3
Q

The Preganglionic neutron and the postganglionic are the __?

A

2-Neuron chain

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4
Q

The chemical messenger produced by the CNS and ANS to communicate with each other (either two neurons/neuron to effective organs)

A

Neurotransmitters

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5
Q

What are the five steps of synaptic transmission?

A

I. Synthesis of transmitters
II. Storage of transmitters
III. Release of transmitters
IV. Binding of transmitters at receptor sites
V. Termination of transmission

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6
Q

What are the three parts of the fifth step of the synaptic transmission?

A

V.A. Reuptake the transmitters
V.B. The enzymatic degradation
V.C. Diffusion away from the gap

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7
Q

Identify if the action is Sympa/Parasympa:
-Dilates bronchioles

A

Sympa

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8
Q

Identify if the action is Sympa/Parasympa:
-Increases salivation

A

Parasympa

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9
Q

Identify if the action is Sympa/Parasympa:
- Dilates blood vessels

A

Parasympa

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10
Q

This theory describes how drugs act through receptors by binding to the receptors to initiate a response or prevent a response (Lock and Key theory)

A

Receptor theory

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11
Q

The drug that produces a response (receptor cells fit the receptor site)

A

Agonist

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12
Q

The drug that blocks a response (does not give the necessary effects)

A

Antagonist

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13
Q

The ____ agonist mimics the effects of the epinephrine/the effects of the SNS (sympatholytic). It stimulates adrenergic receptors

A

Adrenergic

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14
Q

Three categories based on the mechanisms of action of the sympathomimetics:

A

Direct-acting
Indirect-acting
Mixed-acting

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15
Q

Two categories based on chemical structure of the sympathomimetics:

A

Cathecolamines
Noncatecholamines

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16
Q

It blocks alpha and beta receptor blockers

A

Adrenergic blockers

17
Q

The ___ agonist mimics the parasympathetic neurotransmitter acetylcholine (para-sympatholytic)

A

Cholinergic

18
Q

The mnemonic term for adverse reactions for cholinergic agonists

A

DUMBBELS
(Diarrhea, Urination,Miosis and Muscle Weakness, Bronchorrhea, Bradycardia, Emesis, Lacrimation, Salivation/Sweating)

19
Q

The two categories of anti-muscarinics

A

Natural Alkaloids
Synthetic Substitutes

20
Q

The two categories of anti-nicotinics

A

Ganglion blockers
Neuromuscular blockers