Central Nervous System Drugs Flashcards
Which one of the following anti-parkinsonian drugs belongs to COMT inhibitors group?
Tolcapone
Benzodiazepine receptor antagonist. Used as an antidote for benzodiazepine
Flumazenil
Which of the following disorders, administration of barbiturates in contraindicated?
Acute intermittent porphyria
CNS depression, severe metabolic acidosis, nephrotoxicity
Effects of ethylene glycol
All of the following adverse effects are associated with carbamazepine except:
a. Teratogenicity
b. Neurotoxicity
c. Decrease in antidiuretic hormones
d. Hypersensitivity
Decresease in antidiuretic hormones
The state of general anesthesia usually includes _______________.
Loss of consciousness, inhibition of sensory and autonomic reflexes.
.Fomepizole (alcohol DH inhibitor) and hemodialisis
Treatment of alcohol overdose
It binds to gamma subunit of GABA (A) complex to increase frequency of Cl-channel openning; No GABAmimetic activity; BZI mediates sedation; BZ2 mediates antianxiety and impairment of cognitive functions.
Properties of benzodiapines
Alprazolam, diazepam, lorazepam, midazolam, temazepam, oxazepam
Benzodiazepine drugs
It is used for anxiety,phobias, panic attacks.
Uses of alprazolam
Anxiety, preop sedation, muscle relaxation, withdrawal states
Uses of diazepam
Anxiety, preop sedation, status epilepticus
Uses of lozarepam
It is used for preop sedation and anesthesia, anterograde amnesia
Uses of midazolam
Sleep disorders
Uses of temazepam
sleep disorder and anxiety
Uses of oxazepam
