Autonomic Nervous System Drugs Flashcards
It affects the receptors that are normally activated by a natural biochemical found in the body called Acetylcholine
Cholinergic Drugs
One cholinergic drug is ____________. this drug is a cholinergic agonist, It helps to stimulate a certain muscle in the bladder that contacts in order to expel urine.
Bethanechol
The active ingredient of the medication is a potent, selective a-adrenoceptor agonist drug.
Mydriasis - It can be caused by the contraction of the radial fibers of the iris. these smooth muscle cells have a receptor. All the other listed responses are mediated by B adrenoceptors
Which one of the following is the primary neurotransmitter agent normally released in the sinoatrial node of the heart in response to a blood pressure increase?
Acetylcholine - is the transmitter at parasympathetic nerve endings innervating the sinus node (nerve endings of the vagus nerve).
Which of the following is a direct-acting cholinomimetic that is lipid-soluble and is used to facilitate smoking cessation?
Varenicline - is a lipid-soluble partial agonist at nicotinic receptors and is used to reduce craving for tobacco in smokers
It is a prototypical indirect-acting cholinomimetic; It is indirect-acting cholinomimetic; is a quaternary (charged) substance with poor lipid solubility.
Neostigmine
Which of the following is an accepted therapeutic indication for the use of antimuscarinic drugs?
Chronic Obstructive Pulmonary Disease
it is poisoning is associated with parasympathetic blockade.
Botulinum
A man receives a drug that increases cGMP level. Which adverse effect is most likely to result from this medication?
Headache (These drugs cause vasodilation, which may lead to headache, constipation, dry mouth, and sedation are unlikely to be caused by phosphodiesterase inhibitor)
They relax the circular smooth muscles in the iris sphincter and cause dilation of the pupil (Mydriasis)
Muscarinic Antagonists
Which of the following drugs will be useful in treating the symptoms of myasthenia gravis? ( myasthenia gravis is due to the development of antibodies to nicotinic receptors in the patient’s body autoimmune disease)
Anticholinesterase agents
Atropine is one of the ingredients in the antidiarrheal combination diphenoxylate/atropine. Which of the following effects is produced by atropine that contributes to its antidiarrheal effect?
Reduction in gastrointestinal mobility
A patient was administered a neuromuscular blocker (NMB) prior to a surgical procedure to produce skeletal muscle paralysis. the effect of this drug could not reversed with neostgmine. Which of the following neuromuscular blockers was most likely administered to thii patient?
Succinylcholine
________________ NMBs cause muscle fasciculations before causing paralysis and their effects cannot be reversed using cholinesterase inhibitors.
Depolarizing
_________________ NMBs do not cause muscle fasciculations and their effects can be reversed using cholinesterase inhibitors.
Nondepolarizing
